OBJECTIVE To determine the prevalence of cow's milk protein allergy in children with symptoms attributed to cow's milk intake. METHODS Sixty-five children with symptoms attributed to cow's milk intake were studied. Diagnosis was established after an open oral food challenge test carried out at least 15 days after an elimination diet and absence of symptoms, with a follow-up period of up to 4 ...

DESIGN Qualitative case study and mathematical model. SETTING Belgium. OBJECTIVES To evaluate the correlation between the polyamine mean concentration of the milk drunk during the first postnatal month and the appearance of allergy in children who drank this milk. RESULTS A model that describes the dependence of the allergy appearance with the spermine mean concentration of milk drunk dur...

cow’s milk allergy (cma) is the most frequent food allergy in children and oral immunotherapy (oit) is a promising approach for treatment of patients. the most challenging cases are anaphylactic with coexisting asthma and proposing safe protocols is crucial especially in high risk groups. considering that cma varies among patients, an individualized oit protocol would be beneficial to achieve a...

OBJECTIVE A challenge is the recommended test to diagnose cow's milk protein allergy. However, many parents and physicians prefer to not challenge because the procedure may cause (severe) symptoms. In clinical routine, diagnostic testing is only available for IgE-mediated allergy. The aim of this study was to test the diagnostic accuracy of a symptom-based score to select infants at risk of hav...

Many patients feel that their rhinitis is triggered by foods. Although patients with rhinitis are frequently sensitised to foods, there is little evidence to support the role of food allergy in causing rhinitis in isolation. The presence of food allergy in infants may be a marker for subsequent development of allergic rhinitis. While many patients associate the ingestion of cow’s milk with an i...

Methods We examined 50 formulae fed infants 1-12 months old with food allergy. The examination included a collection of allergy history, clinical evaluation and specific methods – the measurement of the coprofiltrate levels of total IgE and allergen-specific IgE to the cow milk protein and casein. The level of total IgE, cow and goat milk proteins IgE allergen-specific antibodies in coprofiltra...

Milk allergy is the most common food allergy among young children, affecting 2% of children and up to 8.4% of those with atopic dermatitis [1,2]. Previously, milk allergic children were advised to strictly avoid foods that contain milk and traces of milk products. However, more recent studies demonstrated that 75% of milk allergic children are able to tolerate extensively heated (baked) milk pr...

The timing of introduction of solid food on the subsequent development of food allergy is under debate and the role of concurrent breastfeeding is unclear. The aim of the present study was to investigate the role of solid food introduction whilst concurrently breastfeeding on food allergy outcome, with a specific focus on cows' milk allergy. Prospectively collected infant feeding data from a bi...

Background: Diagnosis of food allergy is difficult in children. Food allergies are diagnosed using several methods that include medical histories, clinical examinations, skin prick and serum-specific immunoglobulin E (IgE) tests, radio-allergosorbent test (RAST), food challenge, and supervised elimination diets. In this study we evaluated allergies to cow's milk, egg, peanut, and fish in childr...