Recombinant rabies virus (RV)-based vectors have demonstrated their efficacy in generating long-term, antigen-specific immune responses in murine and monkey models. However, replication-competent viral vectors pose significant safety concerns due to vector pathogenicity. RV pathogenicity is largely attributed to its glycoprotein (RV-G), which facilitates the attachment and entry of RV into host...

BACKGROUND Right ventricular (RV) failure is the most important factor of both morbidity and mortality in pulmonary arterial hypertension (PAH). However, the underlying mechanisms resulting in the failed RV in PAH remain unknown. There is growing evidence that angiogenesis and microRNAs are involved in PAH-associated RV failure. We hypothesized that microRNA-126 (miR-126) downregulation decreas...

objectivethis study aimed to assess brain natriuretic peptide in early diagnose of cardiac function in children with congenital heart diseases.methodologythis study was performed on children with chd and healthy. severity of heart failure modified ross classification system was used for grouping patients in four classes. for all participants, height, weight and head circumference were measured....

BACKGROUND Infections by rhinovirus (RV) species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other acute and chronic respiratory diseases. Infections by both species are prevalent in pre-school and school-aged children and, particularly for RV-C, can cause severe symptoms and a need for hospitalization. While associations between RV infect...

The congruence coefficient was first introduced by Burt (1948) under the name of unadjusted correlation as a measure of the similarity of two factorial configurations. The name congruence coefficient was later tailored by Tucker (1951, see also Harman, 1976). The congruence coefficient is also sometimes called a monotonicity coefficient (Borg & Groenen, 1997, p. 203). The congruence coefficient...

OBJECTIVES We sought to determine whether right ventricular (RV) perfusion imaging with technetium99m (Tc-99m) sestamibi or tetrofosmin single-photon emission computed tomography has diagnostic benefit for RV-originated ventricular tachyarrhythmias (RVT). BACKGROUND Identification of RV abnormalities is clinically important to establish RVT etiology. METHODS Forty-seven patients with RVT (23 wi...