DNA ADDUCT BYPASS POLYMERIZATION BY SULFOLOBUS solfataricus DNA POLYMERASE DPO4 ANALYSIS AND CRYSTAL STRUCTURES OF MULTIPLE BASE-PAIR SUBSTITUTION AND FRAMESHIFT PRODUCTS WITH THE ADDUCT 1,N-ETHENOGUANINE Hong Zang‡, Angela K. Goodenough§¶, Jeong-Yun Choi‡, Adriana Irimia, Lioudmila V. Loukachevitch, Ivan D. Kozekov§, Karen C. Angel‡, Carmelo J. Rizzo§, Martin Egli‡, and F. Peter Guengerich‡** ...

Heterotrophic cell suspension cultures of Ruta graveolens were established by reversion of photom ixotrophic cultures without any change in the chemical composition of the growth medium. The heterotrophic cultures were qualitatively and quantitatively analyzed by gaschromatography and mass spectroscopy for volatile compounds. The terpenoid hydrocarbons geijerene and pregeijerene, C6-C8 ketones,...

UNLABELLED Acute Otitis Externa is an inflammation of the outer auditory meatus, and according to popular saying, medicinal plant extracts can be used in its treatment. AIM to assess the in vitro antimicrobial activity of the following plants: Aleolanthus suaveolens; Caryophyllus aromaticus; Cymbopogon citratus; Matricaria chamomila; Pithecellobium avaremotemo; Plectranthus amboinicus and Rut...

We give a new proof of a recent inequality for bicentric quadrilaterals that is an extension of the Euler-like inequality R ≥ √ 2r. A bicentric quadrilateral ABCD is a convex quadrilateral that has both an incircle and a circumcircle. In [6], Zhang Yun called these “double circle quadrilaterals” and proved that

Bernard Lorber, Frédéric Fischer, Marc Bailly, Hervé Roy, and Daniel Kern From the Research team Traduction mitochondriale et pathologies, Architecture et Réactivité de l’ARN, Université de Strasbourg, CNRS, IBMC, 15 rue René Descartes, F-67084 Strasbourg, France Research team Fonctions et dynamiques des nanomachines de l’appareil de traduction, Architecture et Réactivité de l’ARN, Université d...

The antioxidant properties of Ruta graveolens L. were evaluated by two different methods; free radical scavenging using DPPH and inhibition of lipid peroxidation by the ferric thiocyanate method. The IC50 value of the methanol extract in DPPH inhibition was 200.5 μg/mL which was acceptable in comparison with BHT (41.8 μg/mL). In thiocyanate method, the plant extract demonstr...

Ultra low doses used in homeopathic medicines are reported to have healing potential for various diseases but their action remains controversial. In this study we have investigated the antitumour and antimetastatic activity of selected homeopathic medicines against transplanted tumours in mice. It was found that Ruta graveolens 200c and Hydrastis canadensis 200c significantly increased the life...

The effects of some potassium channel blockers on the ionic currents and on the so-called K(+)-depolarization in intact myelinated nerve fibres were studied. 4-AP, and in particular, Flaxedil, proved to be selective K(+)-current blockers. However, TEA, a crown ether (DCH18C6), a longchained triethylammonium compound (C10-TriEA), capsaicin, and the extract from the medicinal herb Ruta graveolens...