background: alzheimer’s disease was known as a progressive neurodegenerative disorder in the elderly and is characterized by dementia and severe neuronal loss in the some regions of brain such as nucleus basalis magnocellularis. it plays an important role in the brain functions such as learning and memory. loss of cholinergic neurons of nucleus basalis magnocellularis by ibotenic acid can commo...

This paper focuses on a time-varying constrained nonconvex optimization problem, and considers the synthesis analysis of online regularized primal-dual gradient methods to track Karush--Kuhn--Tucker (KKT) trajectory. The proposed method is implemented in running fashion, sense that underlying problem changes during execution algorithms. In order study its performance, we first derive continuous...