Some case-control studies have demonstrated that caffeine intake and high CYP1A2 activity increase risks of recurrent pregnancy loss (RPL) but the multifactorial effect is obscure. To investigate whether susceptible women who have more caffeine intake are at high risk of RPL, a case-control study of 58 cases with two or more RPL and fertile 147 controls was performed. The association between da...

Recurrent pregnancy loss (RPL) affects 2-3% of couples. Despite a detailed work-up, the etiology is frequently undefined, leading to non-targeted therapy. Viable embryos and placentae express PreImplantation Factor (PIF). Maternal circulating PIF regulates systemic immunity and reduces circulating natural killer cells cytotoxicity in RPL patients. PIF promotes singly cultured embryos' developme...

BACKGROUND Recurrent pregnancy loss (RPL) defined by two or more failed pregnancies before 20 weeks of gestation. Several factors play a role in RPL including thrombophilic conditions which can be influenced by gene polymorphisms. Plasminogen activator inhibitor-1 (PAI-1) and angiotensin converting enzyme (ACE) genes are closely related to fibrinolytic process, embryonic development and pregnan...

We sought to verify whether variation in the promoter of the gene encoding placental anticoagulant protein annexin A5 (ANXA5) represents a risk factor for recurrent pregnancy loss (RPL). Sequence analysis of 70 German RPL patients, all known to carry neither factor V Leiden nor a prothrombin mutation, revealed four consecutive nucleotide substitutions in the ANXA5 promoter, which were transmitt...

INTRODUCTION Annexin A5 is an essential component of placental integrity that may potentially mediate susceptibility to phenotypes of compromised pregnancy. A promoter haplotype termed M2 of the coding gene ANXA5 has been implicated in various pregnancy complications such as preeclampsia and recurrent pregnancy loss (RPL), however with inconclusive results. STUDY SUBJECTS AND METHODS A retros...

In this brief report, we provide an initial account of the association between love and athletic performance from the perspective of Olympic athletes. We posit that Romantic Passionate Love (RPL) and athletic performance may both involve the reward-motivation system of the brain. Based on this premise, we explored whether activation in one domain (love) might influence the other (sport). Our in...

The advanced metering infrastructure (AMI) is an architecture for two-way communication between electric, gas and water meters and city utilities. The AMI network is a wireless sensor network that provides communication for metering devices in the neighborhood area of the smart grid. Recently, the applicability of a routing protocol for low-power and lossy networks (RPL) has been considered in ...

The purpose of this study is to empirically investigate variation in the migration behaviour across individuals. Both a random parameters logit (RPL) and a standard logit model are employed. The migration models are estimated using a register-based data from Finland. The RPL model proves to be a flexible way to control for random variation in the parameters: the results suggest that many migrat...

Specifying communication routines transparently and explicitly as part of robots’ plans rather than hiding them in separate modules makes robots’ communication behavior more effective, efficient, and robust. It enables robot control systems to generate, reason about and revise their communication behavior. The controllers can also synchronize the robots’ conversations with other actions and use...

This master-thesis engages in the security aspect of the newly introduced IPv6-based routing protocol for low-power and lossy networks RPL. In an analysis of the security of RPL, it is shown that RPL protects against most attacks launched by an adversary that does not have access to the security keys. The major threat lies within an attacker who has compromised these keys and who is consequentl...