Meta-analysis techniques have been widely developed and applied in genomic applications, especially for combining multiple transcriptomic studies. In this paper, we propose an order statistic of p-values (rth ordered p-value, rOP) across combined studies as the test statistic. We illustrate different hypothesis settings that detect gene markers differentially expressed (DE) "in all studies", "i...

Purpose The purpose of this study was to characterize a novel finding that relative positions of choroidal and retinal vessels change over time in preterm infants and to identify factors associated with this finding using quantitative analysis. Methods Fundus images were obtained prospectively through a retinopathy of prematurity (ROP) cohort study. Images were excluded if choroidal vessels c...

using the fixed point theorem in a‎ ‎cone‎, ‎the existence and multiplicity of radial convex solutions of‎ ‎singular system of monge-amp`{e}re equations are established‎.‎

using the fixed point theorem in a‎ ‎cone‎, ‎the existence and multiplicity of radial convex solutions of‎ ‎singular system of monge-amp`{e}re equations are established‎.‎

PURPOSE Retinopathy of prematurity (ROP) is a leading cause of blindness in children with short gestational age and low birthweight. The condition can cause abnormal vessel development that can lead to retinal detachment and blindness. It has been recently reported that a low level of insulin-like growth factor I (IGF-I) is associated with ROP. However, the most prevalent polymorphism of IGF-I ...

A novel design as well as a straight-forward synthesis for a photoswitchable guanidine catalyst is reported. Intense studies of the photochromic properties demonstrated the reversible switchability of its photosensitive azobenzene moiety. Its activity in the ring-opening polymerization (ROP) of rac-lactide was investigated as well. The obtained results are discussed, and an additional guanidine...

PURPOSE To compare infant and retinopathy of prematurity (ROP) characteristics from 3 clinical studies conducted over a 27-year period in the United States. DESIGN Secondary analysis of results of 3 clinical studies. PARTICIPANTS Infants with birth weight (BW) <1251 g. METHODS Analysis of data from the Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) and Early Treatment for Retinopat...

Objectives: This study aimed to investigate the effects of bevacizumab (an anti-VEGF antibody) on structure retina such as thickness nerve fiber layer and macula with optical coherence tomography (OCT) in retinopathy prematurity (ROP) patients. Materials Methods: cross-sectional was conducted 2021-2022 Tabriz, Iran preterm children aged 4-6 years. To this end, a total 300 eyes 150 were assigned...

BACKGROUND/AIMS Telemedicine offers potential to improve the accessibility and quality of diagnosis of retinopathy of prematurity (ROP). The aim of this study was to measure accuracy of remote image based ROP diagnosis by three readers using receiver operating characteristic (ROC) analysis. METHODS 64 hospitalised infants who met ROP examination criteria underwent two consecutive bedside proc...

PURPOSE The Colorado retinopathy of prematurity (ROP) prediction model (CO-ROP), developed using a cohort of infants from Colorado, calls for ROP examination of infants meeting all of the following criteria: gestational age of ≤30 weeks, birth weight of ≤1500 g, and a net weight gain of ≤650 g between birth and 4 weeks of age. The purpose of this study was to perform an external validation to a...