Relationship is one of the most basic needs of human being. When our relationship suffers, we tend to turn to online game as an alternative to fulfill our unmet need. Massive Multi-user Online Role-playing Games (MMORPGs) environment is an ideal platform for multiple players to interact, to make friends, and to complete a task together. Social Learning Theory deposits that behaviors are learned...

Comment on: Tazumi A, et al. Genes Dev 2012; 26:2050-62.

Although trust is widely acknowledged as critical in virtual settings, little is known regarding the antecedents and consequences of trust in leaders of virtual groups. Adopting a multi-level perspective, we propose the leadership’s communication behavior and the broader cultural context in which the group operates determine trust in leaders of virtual groups, which in turn affects the performa...

Pirh2 is a p53 inducible gene that encodes a RING-H2 domain and is proposed to be a main regulator of p53 protein, thus fine tuning the DNA damage response. Pirh2 interacts physically with p53 and promotes its MDM2-independent ubiquitination and subsequent degradation as well as participates in an auto-regulatory feedback loop that controls p53 function. Pirh2 also self-ubiquitinates. Interesti...

INTRODUCTION This study assesses whether demographic and rural-urban variations in dental care service utilization still exist in Taiwan after 15 years of the implementation of universal health insurance coverage, which largely reduces financial barriers to dental care. METHODS The data analysed in this cohort study were based on a random sample of one million beneficiaries retrieved from Tai...

Within the MMORPG World of Warcraft, attitudes towards warfare are expressed in conflicting ways. This is partly a result of the difficult relationship modern Western society has with warfare, and the various political agendas that surround this. Within World of Warcraft, this is expressed specifically in the minigames known as ‘Battlegrounds’, which allow players to fight against each other in...

This study investigated the effectiveness of massive multiplayer online role-playing game (MMORPG)-based (massive multiplayer online role-playing game) instruction in elementary English education. The effectiveness of the MMORPG program was compared with face-toface instruction and the independent variables (gender, prior knowledge, motivation for learning, self-directed learning skills, comput...

Ethanol (EtOH) has effects on numerous cellular molecular targets, and alterations in synaptic function are prominent among these effects. Acute exposure to EtOH activates or inhibits the function of proteins involved in synaptic transmission, while chronic exposure often produces opposing and/or compensatory/homeostatic effects on the expression, localization, and function of these proteins. I...

Though many neuronal cell fate decisions result in reproducible outcomes, stochastic choices often lead to spatial randomization of cell subtypes. This is often the case in sensory systems where expression of a specific sensory receptor gene is selected randomly from a set of possible outcomes. Here, we describe recent findings elucidating the mechanisms controlling color photoreceptor subtypes...