Taguchi’s robust parameter design has been widely applied to a variety of quality engineering problems; however, it is unable to deal with dynamic multiresponse owing to the increasing complexity of the product or design process. This study incorporates desirability functions into a hybrid neural network/genetic algorithm approach to optimize the parameter design of dynamic multiresponses with ...

This article introduces a framework for including different uncertainties at the chemical plant design stage. Through an integrated robust optimization approach and problem formulation, equipment, operating, control, and quality costs are simultaneously taken into account, leading to system, parameter, and tolerance design. Rather than using single pointwise solutions in the decision space, ope...

Two new Bayesian approaches to Robust Parameter Design (RPD) are presented that recompute the optimal control factor settings based on on-line measurements of the noise factors. A dual response model approach to RPD is taken. The first method uses the posterior predictive density of the responses to determine the optimal control factor settings. A second method uses in addition the predictive d...

Synthetic biology has shown its potential and promising applications in the last decade. However, many synthetic gene networks cannot work properly and maintain their desired behaviors due to intrinsic parameter variations and extrinsic disturbances. In this study, the intrinsic parameter uncertainties and external disturbances are modeled in a non-linear stochastic gene network to mimic the re...

A novel approach to robust controller design with hard input constraints is presented. The proposed robust controller design procedure is based on the robust stability condition developed using Affine or Parameter-Dependent Quadratic Stability approach. The obtained feasible design procedures are in the form of BMI or LMI. The obtained design results and their properties are illustrated in simu...

control of production processes in an industrial environment needs the correct setting of input factors, so that output products with desirable characteristics will be resulted at minimum cost. moreover, such systems havetomeetset of qualitycharacteristicstosatisfycustomer requirements.identifyingthemosteffectivefactorsindesignoftheprocesswhichsupportcontinuousandcontinualimprovement isrecently...

How to design a robust gene network to tolerate more intrinsic kinetic parameter variations and to attenuate more extrinsic environmental noises to achieve a desired filtering level will be an important topic for systems biology and synthetic biology. At present, there is no good systematic design method to achieve robust gene network design. In this study, a gene network suffering from intrins...