BACKGROUND It is now widely recognized that radiotherapy of thoracic and chest wall tumors increases the long-term risk of cardiovascular damage although the underlying mechanisms are not fully elucidated. There is increasing evidence that microvascular damage is involved. Endoglin, an accessory receptor for TGF-β1, is highly expressed in damaged endothelial cells and may play a crucial role in...

Department of Chemical & Biological Eng Sheridan Road, Evanston, Illinois 60208, U Department of Chemistry and Interna Northwestern University, 2145 Sheridan E-mail: [email protected]; j-hupp@ NIST Center for Neutron Research, Nationa Gaithersburg, MD 20899, USA. E-mail: tane Department of Materials Science and E Philadelphia, PA 19104, USA † Electronic supplementary information material...

The advent of dual-modality PET/CT imaging has revolutionized the practice of clinical oncology, cardiology and neurology by improving lesions localization and the possibility of accurate quantitative analysis. In addition, the use of CT images for CT-based attenuation correction (CTAC) allows to decrease the overall scanning time and to create a noise-free attenuation map (μmap). The near simu...

Transforming growth factor-B1 (TGF-β1 )and its coreceptor endoglin (ENG) have been shown to contribute to hepatocellular tumor development and malignant progression. Our aim was to evaluate the serum expression levels of ENG/ TGF-β1 mRNAs and risk of hepatocellular carcinoma in cirrhotic Egyptian patients. Our study included 77 subjects. Real time polymerase chain reaction was used to evaluate ...

References 1. Pimlott N. The quiet revolutionary. Can Fam Physician 2014;60:9 (Eng), 10 (Fr). 2. Weston WW, Whitehead C. Why continuity matters. Ian McWhinney’s insights for 21st-century medical education. Can Fam Physician 2014;60:11-3 (Eng), 24-6 (Fr). 3. Pimlott N, Upshur REG. From clinical observation to clinical discovery. The challenge for family medicine research. Can Fam Physician 2014;...

Endoglin (ENG)/CD105 is an essential endothelial cell co-receptor of the transforming growth factor β (TGF-β) superfamily, mutated in hereditary hemorrhagic telangiectasia type 1 (HHT1) and involved in tumor angiogenesis and preeclampsia. Here, we present crystal structures of the ectodomain of human ENG and its complex with the ligand bone morphogenetic protein 9 (BMP9). BMP9 interacts with a ...

Florida International University, Department of Mechanical & Materials Eng. 10555 West Flagler Street, Room EC 3474, Miami, Florida 33174, U.S.A. Federal University of Rio de Janeiro, Department of Mechanical Eng., COPPE, Cid. Universitaria, Cx. Postal 68503, Rio de Janeiro, RJ, 21941-972, Brazil Department of Mechanical and Aerospace Eng., University of Texas at Arlington, Arlington, Texas 787...

Institute of Materials Sci. & Eng.; Center for Nanoscience and Nanotechnology, National Sun Yat-Sen University, Kaohsiung, Taiwan 804, R.O. China Department of Materials Engineering, Shenyang Institute of Aeronautical Engineering, Shenyang, 110034, P.R. China Department of Materials Sci. & Eng., I-Shou University, Kaohsiung, Taiwan 840, R.O. China Department of Materials Sci. & Eng., University...

1 Dept of Global Architecture, Graduate School of Eng., Osaka University, Japan. Email: [email protected] 2 Department of Global Architecture, Graduate School of Eng., Osaka University, Osaka, Japan 3 Department of Architectural Engineering, Graduate School of Eng., Osaka University, Osaka, Japan SYSTEM IDENTIFICATION OF THE BASE ISOLATED STRUCTURE BY PREDICTION ERROR METHOD USING R...

BACKGROUND Preeclampsia is a hypertensive, multi-system pregnancy disorder whose pathophysiology remains unclear. Elevations in circulating soluble endoglin (sENG) and placental/blood ENG mRNA expression antedate the clinical onset of preeclampsia. This study investigated if endoglin (ENG) pathway genetic variation was also associated with the development of preeclampsia. METHODS We used a ca...