Nicotine is considered the main dependence-producing constituent in tobacco products. In analogy with other drugs of abuse, nicotine enhances dopamine (DA) neurotransmission within the mesocorticolimbic DA system. This increase in DA release is thought to be at least partially responsible for the reinforcing and dependence-producing effects of nicotine. However, accumulating evidence suggests t...

In order to address human zinc deficiency, fortifying staple foods with is a safe and cost-effective solution. To ensure the nutritional properties quality of final product, tolerance microorganisms involved in fermentation necessary. Bread, which widely consumed, occupies substantial place many people’s diets, often based on sourdough making process; thus, it might be an important headlining p...

BACKGROUND Growth arrest and DNA-damage-inducible protein 45β reactivates methylation-silenced neural plasticity-associated genes through DNA demethylation. However, growth arrest and DNA-damage-inducible protein 45β-dependent demethylation contributes to neuropathic allodynia-associated spinal plasticity remains unclear. METHODS Adult male Sprague-Dawley rats (654 out of 659) received a spin...

ABSTRACT We use deep imaging from the Dark Energy Camera to explore peripheral regions of nine globular clusters in outer halo Milky Way. Apart Whiting 1 and NGC 7492, which are projected against Sagittarius stream, we see no evidence for adjacent stellar populations indicate any these is associated with coherent tidal debris a destroyed host dwarf. also find tails around our sample; however, b...

Abstract Lumpfish is used to control sea lice in open net-pen farming of Atlantic salmon, but little known about their nutritional requirements. The aim this study was investigate the effects replacing marine oil (MO) with rapeseed (RO), diets incorporating 50 % plant protein concentrates, on growth, chemical and fatty acid (FA) composition juvenile lumpfish. Four extruded diets, nearly iso-lip...