The variability of gene expression signatures across tumor sites has been previously documented [Stewart et al. 2017]. However, how this information can be exploited in practice is less obvious. To better understand the links between gene-based risk scores and sampling, we performed morphology-based RNA extraction studied scores' their relative prognostic value comparison with whole-tumor sampl...

Abstract Background Monomorphic ventricular tachycardia (VT) is a potentially life-threatening condition. Although radiofrequency catheter ablation represents an effective treatment method for many of these patients, significant variability observed in postprocedural mortality, which attributable to multiple factors, including the high burden comorbidities. Therefore, there great demand accurat...

Several risk stratification instruments for postoperative delirium in older people have been developed because early interventions may prevent delirium. We investigated the performance and agreement of nine commonly used risk stratification instruments in an independent validation cohort of consecutive elective and emergency surgical patients aged ≥50 years with ≥1 risk factor for postoperative...