This research examines the validity of utilising a 2D multiplane FDTD acoustic model to simulate low frequency sound propagation as part of a hybrid room impulse response (RIR) synthesis system. Analytic results, pertaining to the comparison of simulated low frequency multiplane RIRs with both practical RIR measurements and 3D FDTD simulated RIRs, demonstrate that a good level of accuracy is at...

Room impulse responses (RIRs) are very commonly used to represent the acoustic response of rooms for the derivation of acoustical parameters and for auralization. This paper presents a set of signal processing techniques that can be used to enhance the usefulness of recorded RIRs for convolution-based room simulations (which could be classed as a type of auralization), which include using the n...

Recent work into 3D audio reproduction has considered the definition of a set of parameters to encode reverberation into an object-based audio scene. The reverberant spatial audio object (RSAO) describes the reverberation in terms of a set of localised, delayed and filtered (early) reflections, together with a late energy envelope modelling the diffuse late decay. The planarity metric, original...

Connector enhancer of KSR (CNK), an essential component of Drosophila receptor tyrosine kinase/mitogen-activated protein kinase pathways, regulates oppositely RAF function. This bimodal property depends on the N-terminal region of CNK, which integrates RAS activity to stimulate RAF and a bipartite element, called the RAF-inhibitory region (RIR), which binds and inhibits RAF catalytic activity. ...

Rev1 is a translesion synthesis (TLS) DNA polymerase essential for DNA damage tolerance in eukaryotes. In the process of TLS stalled high-fidelity replicative DNA polymerases are temporarily replaced by specialized TLS enzymes that can bypass sites of DNA damage (lesions), thus allowing replication to continue or postreplicational gaps to be filled. Despite its limited catalytic activity, human...

The transcription factors nuclear factor of activated T cells (NFAT) and activator protein 1 (AP-1) coordinately regulate cytokine gene expression in activated T-cells by binding to closely juxtaposed sites in cytokine promoters. The structural basis for cooperative binding of NFAT and AP-1 to these sites, and indeed for the cooperative binding of transcription factors to composite regulatory e...

BACKGROUND To evaluate the geometrical differences of target volumes propagated by deformable image registration (DIR) and rigid image registration (RIR) to assist target volume delineation between diagnostic Positron emission tomography/computed tomography (PET/CT) and planning CT for primary esophageal cancer (EC). METHODS Twenty-five patients with EC sequentially underwent a diagnostic F-f...

Genetic heterogeneity was investigated using 24 microsatellite markers and genomic DNA of randomly selected birds from the control lines RIR chicken maintained at ICAR-Central Avian Research Institute, Izatnagar. The alleles were determined on urea-PAGE, recorded GelDoc system samples genotyped. complete genotypic data set analyzed POPGENE software. observed heterozygosity (Ho) means 0.6306±0.3...

Single-channel late reverberation suppression algorithms need estimates of the late reverberance spectral variance (LRSV) in order to suppress the late reverberance. Often the LRSV estimators are derived from a statistical room impulse response (RIR) model. Usually the late reverberation is modeled as a white Gaussian noise sequence with exponentially decaying variance. The whiteness assumption...