3-Formyl-4-hydroxyphenylguanidine hydrochloride and its Schiff base copper(II), zinc(II), and iron(III) chelates were synthesized and their inhibitory activity against bovine beta-trypsin were determined. Syntheses of Schiff base metal chelates were carried out from 3-formyl-4-hydroxyphenylguanidine, various L-amino acids, and divalent metal acetate. Their structures were established on the bas...

New coordination complexes of Co, Ni and Zn with Schiff base N’-((2-thioxo-1,2-dihydroquinoline-3yl)methylene) pyridine-4-carbohydrazide have been synthesized and characterized by several techniques using elemental analysis (C, H, N), IR spectra and 1HNMR spectra. The new Schiff base has been synthesized by the reaction of pyridine-4-carbohydrazide and 2-thioxo-1,2dihydroquinoline-3-carbaldehyd...

The application of an external electric field to dry films of Asp-85-->Asn mutant bacteriorhodopsin causes deprotonation of the Schiff base, resulting in a shift of the optical absorption maximum from 600 nm to 400 nm. This is in marked contrast to the case of wild-type bacteriorhodopsin films, in which electric fields produce a red-shifted product whose optical properties are similar to those ...

The transcriptase activity of influenza A virus ribonucleoproteins was inhibited by 42 to 49% in vitro in the presence of membrane (M) protein. The addition of M protein to the system of ribonucleoprotein preparations isolated from rimantadine-sensitive or rimantadine-resistant influenza virus strains, as well as the addition of M protein isolated from a sensitive strain, in the presence of rim...

The complexes of Fe(II), Mn(II) and Ni(II) with a combination of a Schiff base, nitrogen-donor ligand or macrocyclic ligand and trithiocyanuric acid (ttcH3) were prepared and characterized by elemental analysis and spectroscopies. Crystal and molecular structures of the iron complex of composition [Fe(L1)](ttcH2)(ClO4)·EtOH·H2O (1), where L1 is Schiff base derived from tris(2-aminoethyl)amine a...

In an effort to develop new antibacterial drugs, some novel bisindolylmethane derivatives containing Schiff base moieties were prepared and screened for their antibacterial activity. The synthesis of the bisindolylmethane Schiff base derivatives 3-26 was carried out in three steps. First, the nitro group of 3,3'-((4-nitrophenyl)-methylene)bis(1H-indole) (1) was reduced to give the amino substit...

The title compound, C(28)H(20)N(2)O(2)·2H(2)O, comprises a Schiff base mol-ecule with an imposed inversion centre in the middle of p-phenyl-enediamine unit and water mol-ecules of crystallization. In the structure, the Schiff base mol-ecule is present as the keto-amino tautomer with a strong intra-molecular N-H⋯O hydrogen bond. The Schiff base mol-ecules and water mol-ecules of crystallization ...

Risky sexual behavior (RSB) is associated with a variety of negative health and social consequences including STDs and unplanned pregnancies. The present study focused on the association between psychopathic personality traits and RSB. College students (N = 511) completed self-report measures of RSB, psychopathic personality traits, and sensation seeking. When sensation seeking, Fearless Domina...

BACKGROUND Amantadine hydrochloride and rimantadine hydrochloride are recommended by the Centers for Disease Control and Prevention for prophylaxis of influenza A. While data suggest that rimantadine is better tolerated, there are no data examining the rate of adverse reactions in elderly patients who receive amantadine vs rimantadine. Our objective was to assess the adverse reaction rate in el...

A novel Schiff base was synthesized by the reaction of piperonal and anthranilic acid, which was further utilized in the synthesis of five novel complexes by reaction with different metal salts ultrasonically. Time for the reaction was greatly reduced through ultrasound irradiations and the yield of reactions was also high as compared to the conventional methods using reflux conditions. The...