This study aimed to assess genetic diversity within and between nine Vietnamese local chicken breeds and two Chinese breeds included for comparison. Genotyping 29 microsatellites revealed high diversity of both Vietnamese and Chinese breeds. Cluster analysis using the STRUCTURE software suggested six clusters as the most likely grouping of the 11 breeds studied. These groups encompassed four ho...

Abstract Sustainable modern poultry production depends on effective protection against infectious diseases and a diverse range of antibodies is key for an immune response. In the domestic chicken, somatic gene conversion dominant process in which antibody immunoglobulin genes are diversified. Affinity maturation by hypermutation (SHM) also occurs, but relative contribution versus to (Ig) divers...

Vittal P. Prakash, Lindsay LeBlanc, Nicole E. Alexander-Scott, Jaclyn Skidmore, Deanna Simmons, Daniela Quilliam, Kimberle C. Chapin Department of Pathology, Rhode Island Hospital, Department of Pathology and Laboratory Medicine, Warren Alpert Medical School of Brown University, Rhode Island Department of Health, Division of Pediatric/Adult Infectious Diseases, Warren Alpert Medical School of B...

Oxygen is one of the critical determinants for normal embryonic and fetal development. In avian embryos, lack of oxygen will lead to high fetal mortality, heteroplasia, and cardiovascular dysfunction. Tibetan chicken is a breed native to Tibet that could survive and keep higher hatchability regardless of negative effects of hypoxia. Generally, adaptive animals in high altitudes are characterize...

Multicenter clinical research studies are often needed to address issues of generalizability, conditions with low incidence, adequate statistical power, and potential study bias. While pediatric research networks began work in the 1950s, and Rhode Island physicians have contributed to many of these studies, pediatric emergency medicine (PEM) collaboratives are relative newcomers. Since the mid-...

Primers were used to amplify a 561-bp region of the 16S rRNA gene of Ehrlichia phagocytophila from Ixodes scapularis ticks and small mammals collected in Rhode Island and Connecticut. DNA sequences for all 50 E. phagocytophila-positive samples collected from 1996 through 1998 in southwestern Connecticut were identical to the sequence reported for E. phagocytophila DNA from confirmed human cases...