The role of the cytoplasmic loops and C-terminal region of bovine rhodopsin (Rho) in binding and activating rhodopsin kinase was investigated. The ability of various enzymatically truncated forms of photolyzed rhodopsin (Rho*) to stimulate rhodopsin kinase activity was quantified. Following endopeptidase Asp-N cleavage of all phosphorylation sites on the C-terminal, the resulting truncated Rho*...

The present study aimed to investigate the changes of Rho-associated kinase (Rho-kinase) and neuronal nitric oxide synthase (nNOS) expression in age-associated erectile dysfunction (ED) in Sprague-Dawley (SD) rats. A total of 100 intact male SD rats were divided into 20 groups according to their age (5-24 months; rats that were the same age in months were in the same group). Erectile response m...

Transcription termination protein Rho of Escherichia coli interacts with newly synthesized RNA chains and brings about their release from elongation complexes paused at specific Rho-dependent termination sites. Rho is thought to accomplish this by binding to a specific Rho "loading site" on the nascent RNA and then translocating preferentially along the transcript in a 5'-->3' direction. On rea...

In late gestation, enhanced myometrial contractility is mediated in part through increased Rho/Rho kinase. Since leptin, which is elevated in pregnancy and obesity, can directly depress myometrial function, we hypothesized that in leptin receptor-deficient mice, myometrial contractility would be greater in late pregnancy due to increased Rho/Rho kinase activity. To test this, we correlated RhoA...

Rhodopsin (Rho) resides within internal membrane structures called disc membranes that are found in the rod outer segments (ROS) of photoreceptors in the retina. Rho expression is essential for formation of ROS, which are absent in knockout Rho-/- mice. ROS of mice heterozygous for the Rho gene deletion (Rho+/-) may have a lower Rho density than wild type (WT) membranes, or the ROS structure ma...

For a split reductive group $G$ over number field $k$, let $\rho$ be an $n$-dimensional complex representation of its dual $G^\vee(\mathbb{C})$. any irreducible cuspidal automorphic $\sigma$ $G(\mathbb{A})$, where $\mathbb{A}$ is the ring adeles in \cite{JL21}, authors introduce $(\sigma,\rho)$-Schwartz space $\mathcal{S}_{\sigma,\rho}(\mathbb{A}^\times)$ and $(\sigma,\rho)$-Fourier operator $\...

Background: Katz Index is a well-known index for assessing basic activities of daily living. The aim was to determine validity and reliability of the Katz Index in Iranian patients with acute stroke. Methods: Eighty-seven patients (56 male, 31 female) with acute stroke (1-30 days post-stroke) participated in this psychometric properties study. Interval time for retest was 14 days. All partic...

Based on their Rho binding motifs several Rho target molecules can be classified into three groups; class I includes the protein kinase PKN, rhophilin, and rhotekin, class II includes the protein kinases, Rho-associated coiled-coil containing protein kinases, ROCK-I and ROCK-II, and class III includes citron. Taking advantage of the selectivity in recognition by these targets between Rho and Ra...

Consider an entire (absolutely convergent in $\mathbb{C}$) Dirichlet series $F$ with the exponents $\lambda_n$, i.e., of form $F(s)=\sum_{n=0}^\infty a_ne^{s\lambda_n}$, and, for all $\sigma\in\mathbb{R}$, put $\mu(\sigma,F)=\max\{|a_n|e^{\sigma\lambda_n}:n\ge0\}$ and $M(\sigma,F)=\sup\{|F(s)|:\operatorname{Re}s=\sigma\}$. Previously, first authors M.M.~Sheremeta proved that if $\omega(\lambda)...