BACKGROUND Chronic rhinosinusitis with nasal polyps is characterized by local inflammation and is categorized into two subtypes in Japan: eosinophilic chronic rhinosinusitis, and non-eosinophilic chronic rhinosinusitis. The objective of this study was to investigate the expression of key transcription factors for Treg and Th1/Th2/Th17 cells, in relation to the mRNA expression of representative ...

background chronic rhinosinusitis is an inflammatory-infectious disease involved paranasal sinuses as a common site of microbial pathogens and infections in patients suffering from the disease. the disease is labeled chronic when it lasts for more than 12 weeks. objectives as these infections constitute an important cause of morbidity it can be a strong life-threatening factor, in this investig...

Introduction: There are more and studies that demonstrate the anti-inflammatory effects of traditional Mediterranean diet (TMD). The aim study was to assess an intervention with TMD in patients recurrent acute chronic rhinosinusitis. Material Methods: We performed a pretest–posttest comparison 114 (56 girls 58 boys) aged one five years who had three or rhinosinusitis episodes period 1 year. The...

Background Sinonasal disease is prevalent and impacts on quality of life, the Modified SNOT-20 (MSNOT-20) questionnaire aims to provide a complete assessment of rhinitis /rhinosinusitis and its impact. Following a pilot study evaluation, the main project assessed the prevalence of rhinitis/rhinosinusitis in a community based survey in Farnborough, UK. A sub group was invited for clinical examin...

Corticosteroids are the mainstay of treatment for refractory chronic rhinosinusitis. The off-label use of steroid-eluting stents has increasingly gained popularity in functional endoscopic sinus surgery for decreasing postoperative inflammation and synechiae formation. However, there is a paucity of data outlining the safety profile of this device despite its widespread use. This study was desi...

OBJECTIVE To assess the significance of the Streptococcus anginosus group in intracranial complications of pediatric patients with rhinosinusitis. DESIGN Retrospective cohort study. SETTING Tertiary pediatric hospital. PATIENTS A 20-year review of medical records identified patients with intracranial complications resulting from rhinosinusitis. In the 50 cases identified, S anginosus was ...

OBJECTIVE To determine if patients undergoing revision endoscopic sinus surgery (ESS) for chronic rhinosinusitis obtain significant symptomatic benefit from surgery. DESIGN Prospective controlled clinical trial. METHODS Adult patients undergoing revision ESS were evaluated preoperatively with a computed tomographic scan and the Rhinosinusitis Symptom Inventory. After the revision ESS, patie...

Summary Rhinitis and sinusitis usually coexist and are concurrent in most individuals; thus, the correct terminology is now "rhinosinusitis". On the basis of numerous causative factors, often co-existing in the same patient, the diagnosis of rhinosinusitis is also made by a wide variety of practitioners (allergologists, otolaryngologists, pulmonologists, primary care physicians, paediatricians,...

Fungal Rhinosinusitis (FRS) is a well known entity, but only in more recent times have the types of FRS been more fully defined. In this study, we evaluate the diagnosis of FRS in a single medical center. Cases were divided into 2 main categories, non-invasive and invasive. Non-invasive FRS included fungus ball (FB) and allergic fungal rhinosinusitis (AFRS). Invasive FRS included acute invasive...