OBJECTIVE Body fat is an important source of hormones and cytokines (adipokines) that not only regulate the energy balance, but also regulate the inflammatory and immune responses. This study investigated the association of clinical conditions with serum levels of adipokines in patients with rheumatoid arthritis. METHODS Serum levels of resistin, leptin, and adiponectin were measured by enzym...

OBJECTIVE Resistin increases insulin resistance (IR) in mice. However, the role of resistin in human disease remains controversial. We aimed to assess plasma resistin levels and their associations with inflammatory and fibrinolytic markers, IR and metabolic syndrome (MetS) among Chinese. DESIGN AND METHODS Plasma resistin was measured in a population-based cross-sectional survey of 3193 Chine...

Resistin is a secretory adipokine with proinflammatory properties in humans [1]. It has emerged during this decade as a promising inflammatory marker in various diseases [2]. This study aimed to investigate the role of serum resistin as a marker of disease activity in inflammatory bowel disease (IBD) and its correlation with clinical, endoscopic, histological and inflammatory parameters of IBD....

UNLABELLED Resistin is a recently discovered signal molecule, which could help elucidation of the pathophysiology of the insulin resistance and its correlation with obesity. As little information was available about resistin determination in venous blood at the time of our study, we focused on the question whether any correlation exists between persons with type 2 diabetes mellitus, with system...

OBJECTIVE Adiponectin and resistin, two recently discovered adipocyte-secreted hormones, may link obesity with insulin resistance and/or metabolic and cardiovascular risk factors. We performed a cross-sectional study to investigate the association of adiponectin and resistin with inflammatory markers, hyperlipidemia, and vascular reactivity and an interventional study to investigate whether ato...

The aim of our study was to evaluate the influence of surgical removal of pheochromocytoma on the endocrine function of adipose tissue and subclinical inflammation as measured by circulating C-reactive protein (CRP) levels. Eighteen patients with newly diagnosed pheochromocytoma were included into study. Anthropometric measures, biochemical parameters, serum CRP, leptin, adiponectin and resisti...

INTRODUCTION The purpose of this study was to evaluate and compare the serum levels and local expression of resistin in patients with idiopathic inflammatory myopathies to controls, and to determine the relationship between resistin levels, inflammation and disease activity. METHODS Serum resistin levels were determined in 42 patients with inflammatory myopathies and 27 healthy controls. The ...

adipose tissue secretes a large number of adipocytokines such as leptin, resistin, and adiponectin. many of these hormones and cytokines are altered in obese individuals and may lead to disruption of the normal balance between cell proliferation, differentiation, and apoptosis. the aim of our work was to investigate the disturbance of secretion of adiponectin and resistin in de novo and relapse...

The aim of the present study was to detect the expression of resistin in rats with acute pancreatitis (AP) and investigate its significance in the pathogenesis of AP. In total, 40 Sprague-Dawley rats were randomly divided into four groups (n=10), including the normal control, sham-operated, acute edematous pancreatitis (AEP) and acute necrotizing pancreatitis (ANP) groups. Following the establi...