Condition-Based Maintenance (CBM) optimization using Proportional Hazards Model (PHM) is a kind of maintenance optimization problem in which inspections of a system relevant to its failure rate depending on the age and value of covariates are performed in time intervals. The general approach for constructing a CBM based on PHM for a system is to minimize a long run average cost per unit of time...

THINK Surgical TSolution-One® is an active-autonomous, image-based, robotic milling system which enables the surgeon to attain a consistently accurate implant component positioning. The TSolution-One® system is capable of achieving this through an image-based preoperative planning system which allows the surgeon to create, view and analyse the surgical outcome in 3D. The accuracy and precision ...

OBJECTIVE The cost-effectiveness of renal replacement therapy (RRT) is affected by the composition of treatment. This study aimed to estimate the costs and outcomes associated with changing the composition of RRT modality over time. METHODS By using clinical and cost data from a systematic review, a Markov model was developed to assess the costs and benefits of the four main treatments availa...

The purposes of this study were to examine the cost-effectiveness of this technology and to determine improvements in patient outcome needed to make custom total knee cutting blocks cost-effective. A Markov decision model was used to evaluate the cost-effectiveness of custom cutting blocks compared with traditional instrumentation in total knee arthroplasty. The analysis demonstrates routine us...

BACKGROUND Tranexamic acid (TXA) has been associated with decreased blood loss and transfusion after total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose of this study was to examine both transfusion utilization and the economic impact of a Process Improvement Project implementing TXA for THA and TKA. METHODS After standardization of TXA administration in THA and TKA pa...

In this research, a model for optimal PM planning based on reliability is developed and solved for multi-component systems. In the proposed model, the type of PM actions for each inspection period is determined in such manner that the total weighted related costs are minimized while a minimum required system reliability is maintained. The planning horizon is divided into some inspections interv...