recurrent pregnancy loss (rpl) is a multifactorial disorder that remains idiopathic in 50% of the cases. the aim of this study was to investigate the association between mthfd1 as well as enos polymorphisms with idiopathic rpl. in a case-control study, 100 women with idiopathic recurrent pregnancy loss (prl) and 50 controls referred to noor laboratory, khoozestan, iran, were evaluated. genotypi...

. gynaecological practice. Treatment may be prolonged and is frequently disapr ]nting. The loss of potential citizens is probably of the order of one in every three ? ^gnancies. The woman is often deeply disappointed at the outcome of her pregnancy ^ j when her loss is repeated on three or more occasions she may indeed feel desperate. ny doctors are of the opinion that treatment is of no great ...

In recent decades, the association between a hypercoagulable state and its causes and adverse pregnancy outcome, in particular recurrent pregnancy loss (RPL) has been studied extensively. Although the first studies were focused only on the association between thrombophilia and RPL, subsequent studies underlined also a potential role of antithrombotic treatment to prevent vascular complication s...

Inherited thrombophilias have been suggested as a possible condition of increased susceptibility to adverse pregnancy outcomes. Although there is no consensus on the association between the factor V Leiden mutation and early (less than 10 weeks) pregnancy loss, the evidence suggests an association between the mutation and second-, and third-trimester fetal loss and severe preeclampsia. At prese...

Discriminant analysis (DA) encompasses procedures for classifying observations into groups (i.e., predictive discriminative analysis) and describing the relative importance of variables for distinguishing amongst groups (i.e., descriptive discriminative analysis). In recent years, a number of developments have occurred in DA procedures for the analysis of data from repeated measures designs. Sp...

Routine investigation for recurrent pregnancy loss includes measurement of antiphospholipid antibodies under the perception that the lupus anticoagulant (LAC) is prevalent in this population. Our tertiary clinic sees ~250 new patients with recurrent pregnancy loss annually, in addition to those with systemic lupus erythematosus and/or antiphospholipid syndrome. We measure LAC using a 4-assay pa...