background bk virus (bkv) belongs to the human polyomaviridae and the primary bkv infection is occurred during childhood then the virus could be latent through life, especially in the kidneys and urinary system. it became reactive after an immunocompromised status, such as pregnancy or transplantation. isolated bkv from different locations of the world is grouped into four subtypes using serolo...

We have previously shown, in renal transplant recipients on maintenance immunosuppression, that a whole-blood assay was superior in detecting immunity towards purified protein derivative (PPD) compared with skin testing. As blood tests may have limitations during high-dose immunosuppression therapy, the present study was aimed at characterising the effect of high immunosuppressive drug levels o...

As morbidity and mortality from graft dysfunction and failure after kidney transplantation have declined, transplant-related malignancies have become one of the most significant sources of posttransplant complications. Currently, cancer is a major factor limiting the life expectancy of kidney transplant patients, and cancer management is now a crucial component of their medical care. This paper...

Renal transplantation is currently the preferred treatment modality for virtually all suitable candidates with end-stage renal disease. When compared with the general population, cardiovascular mortality in transplant recipients is increased by nearly 10-fold among patients within the age range of 35 and 44 and at least doubled among those between the ages of 55 and 64. All transplant recipient...

BACKGROUND Urinary tract infection is the most common infectious disease requiring hospitalisation following renal transplantation. However, the risk and outcome of post-transplant pyelonephritis remains unclear. METHODS This population-based cohort study was conducted from 1 January 1990 to 31 December 2009. Each member of a Danish population-based, nationwide cohort of first-time renal tran...

Influenza can cause significant morbidity and mortality in renal transplant recipients especially with a high rate of lower respiratory disease. Annual influenza vaccination is therefore recommended to renal transplant recipients. We report the first three cases of acute kidney injury in renal transplant recipients following influenza vaccination that all led to graft loss. They all had differe...

New-onset diabetes after transplantation (NODAT) is a common comorbidity after renal transplantation. Though metformin is the first-line agent for the treatment of type 2 diabetes, in renal transplant recipients, metformin is frequently avoided due to concerns about renal dysfunction and risk for lactic acidosis. Therefore, alternative first-line agents for the treatment of NODAT in renal trans...

'die presence anil significance of hepatitis c virus infection among patients with chronic renal failure (crf) on hemodialysis and renal transplant recipient were evaluated a pcrioil of 30 months. a total of 125 patients, comprising 25 recieving chronic hemodialysis, 47 renal transplant candidates and 5.1 renal transplant recipients, were studied with a second generation immunoassay (elisa ii)....

background: primary infection with bk virus (bkv) is occurred during childhood and usually asymptomatic, but after initial infection, bkv may persist lifelong in the kidney and genitourinary tract. reactivation may occur in individuals with compromised immunity such as renal transplant recipients. due to the role of bkv in bk virus-associated nephropathy (bkvan) and potentially renal allograft ...