The applicability, feasibility, reproducibility, and accuracy of the method of measuring regional cerebral blood flow using ultrafast computed tomography were evaluated in 25 dogs under varying physiological and pathophysiological conditions. Regional cerebral blood flow values were 75.6 +/- 29.4 ml/100 g/min (mean +/- standard deviation) for the hemisphere, 68.4 +/- 28.2 ml/100 g/min for the b...

This study assesses the relationship between the distribution of thallium-201 and myocardial blood flow during coronary vasodilation induced by intravenous dipyridamole in canine models of partial and complete coronary artery stenosis. 10 dogs were chronically instrumented with catheters in the left atrium and aorta and with a balloon occluder and electromagnetic flow probe on the proximal left...

sion. Arch Intern Med 133: 916-929, 1974 34. Bohr DF: Angiotensin on vascular smooth muscle. In Angiotensin, edited by IH Page, FM Bumpus. New York, Springer-Verlag, 1974, pp424-428 35. Williams GH, HollenbergNK, Braley LM: Influence of sodium intake on vascular and adrenal angiotensin II receptors. Endocrinology 98: 1343-1350, 1976 36. Fray FCS, Johnson MD, Barger AC: Renin release and pressor...

Intracranial optic nerve blood flow was measured by the radiolabeled microsphere technique in 30 adult sheep under light barbiturate anesthesia. Regional blood-flow rates were determined under basal conditions. The responses of regional blood flow to alterations in PaCO2 and to changes in arterial blood pressure were also measured. Under basal conditions blood flow was comparable to that found ...

Walshe, iMl.D., D.Sc., F R.S. Tenth Edition. (Pp. xii + 381; figs. 60. 35s.) Edinburgh and London: E. & S. Livin.gstone, 1963. THiE appeartanice of the tenth editioni of this textbook twenty-threc years since it was first published reflects its great pol)Ulllarity. The author alludes in the prefatce that its reviewers would probably not be drawn from the ranks of those to vholom the 1)ook is pa...

Neural networks have been successfully applied to brain perfusion images to classify patients with Alzheimer's disease from normal or other patient populations. Given the recognition that Alzheimer's disease constitutes a heterogeneous disorder, the identification of subgroups sharing common functional brain deficits would constitute a further improvement in the utility of such methods. Therefo...

BACKGROUND AND PURPOSE Cerebral hypoperfusion has occasionally been reported during essential hypertension. We explored regional cerebral blood flow in a large series of neurologically asymptomatic hypertensive patients to determine relations among cerebral blood flow, concomitant main vascular risk factors, and the most common signs of end-organ damage. METHODS Regional cerebral blood flow w...

Near-infrared spectroscopy (NIRS) has been widely used as a non-invasive method to measure brain activity, but it is corrupted by baseline drift noise. Here we present a method to measure regional cerebral blood flow as a derivative of NIRS output. We investigate whether, when listening to languages, blood flow can reasonably localize and represent regional brain activity or not. The prefrontal...

not previously been satisfactory clinical methods for tissue flow measurement. Recent techniques with radio-isotopes which can be used in man are therefore of interest, and this editorial reviews generally the theory underlying their use and their application in the past few years. The great advantage of radio-isotopes is that they may be measured easily in the body using an external detector, ...

Regional cerebral blood flow was measured by the 133-xenon inhalation method during resting in 38 healthy men and 38 healthy women matched pairwise for age in the range 18-72 years. The results showed 11% higher global flow level in the women in all ages. A similar and significant regression of flow by age was seen for both sexes. The regional flow distribution also showed some sex-related diff...