By using a Langendorff-perfused ring of anisotropic rabbit epicardium, sustained reentrant ventricular tachycardia with a cycle length of 168 +/- 13 msec (n = 26) was induced by programmed electrical stimulation. Continuous left ventricular epicardial mapping with 256 simultaneously recorded unipolar electrograms demonstrated that the tachycardia was based on circuital movement of the impulse a...

Several large evaluations of correctional programs across the United States have found that offender assessment is one of the most poorly implemented principles of effective offender intervention. Correctional programs have relied too much on subjective, clinical assessments of offenders’ likelihood of re-offending or risk, and specific risk factors. Corrections programs have neglected one of t...

The scientific study of wrongful convictions has been ongoing for the past few decades. These studies have worked to quantify convictions, identify contributing factors, and understand negative implications society individuals who experiences a incarceration. majority existing focus on what leads conviction, with fewer examining community reentry processes wrongfully convicted individuals. Thos...

PURPOSE To present a technique that creates a neofenestration in the dissecting lamella of chronic aortic dissections using standard or intravenous ultrasound (IVUS)-guided reentry devices. TECHNIQUE To create a neofenestration, a standard or IVUS-guided reentry device is deployed in either the true or false aortic lumen while a balloon is simultaneously inflated in the opposite lumen to stab...

Electrical pacing is a common procedure in both experimental and clinical settings to study and/or annihilate anatomical reentry. A previous study [Comtois and Vinet, Chaos 12, 903 (2002)] has described new ways to terminate reentry in a one-dimensional loop model by a protocol consisting of only two stimulations. Annihilation of the reentrant activity was much more likely with these new scenar...

AIMS Acute ischemia is a major cause of sudden arrhythmic death, further promoted by potassium current blockers. Macro-reentry around the ischemic region and early afterdepolarizations (EADs) caused by electrotonic current have been suggested as potential mechanisms in animal and isolated cell studies. However, ventricular and human-specific arrhythmia mechanisms and their modulation by repolar...

OBJECTIVE Attempts to cardiovert tachycardia by rapid point pacing can sometimes result in transient or stable increase of the heart rate (acceleration), changed ECG morphology, and/or fibrillation. The goal of this study was to investigate the effect of rapid pacing on the dynamics of functional reentry in monolayer cultures of cardiac cells. METHODS Fully confluent, uniformly anisotropic mo...

BACKGROUND Heart failure is operationally defined as the inability of the heart to maintain blood flow to meet the needs of the body and it is the final common pathway of various cardiac pathologies. Electrophysiological remodeling, intercellular uncoupling and a pro-fibrotic response have been identified as major arrhythmogenic factors in heart failure. OBJECTIVE In this study we investigate...

Phase-2 reentry is a basic mechanism for the transition to VT and VF in the heart. It is thought to underly many causes of idiopathic ventricular arrhythmias as, for instance, those occurring in Brugada syndrome. Reentry is usually linked to heterogeneity in tissue repolarization. We study some circumstances under which a region of depolarized tissue can reexcite adjacent regions that exhibit s...

Of the many direct numerical methods, the pseudospectral method serves as an effective tool to solve the reentry trajectory optimization for hypersonic vehicles. However, the traditional pseudospectral method is time-consuming due to large number of discretization points. For the purpose of autonomous and adaptive reentry guidance, the research herein presents a multistage trajectory control st...