نتایج جستجو برای: reduced glutathione

تعداد نتایج: 617805  

Journal: :Bioscience reports 1983
R L Singhal R Vijayvargiya

Glutathione content and the activity of glutathione reductase were examined in ventral prostate and chemically induced 11095 squamous-cell prostatic carcinoma in rats. Castration produced a significant reduction in the levels of reduced (GSH) and oxidized (GSSG) glutathione and glutathione reductase activity in the prostate. Replacement of testosterone (50 mg/kg) daily for 7 days to castrated a...

Journal: :The Journal of clinical investigation 1964
A S HILL A HAUT G E CARTWRIGHT M M WINTROBE

A deficiency of reduced glutathione in erythrocytes of freshly shed blood (1-4) or in erythrocytes exposed to certain chemical compounds (5) has been associated with shorter red cell survival and, in most cases, with the accumulation of oxidation products of hemoglobin, including methemoglobin, sulfhemoglobin, and Heinz bodies. Studies of "primaquine-sensitive" hemolytic disease have emphasized...

Journal: :avicenna journal of phytomedicine 0
jude efiom okokon department of pharmacology and toxicology, faculty of pharmacy, university of uyo, uyo, nigeria joseph oyepata simeon department of pharmacology and toxicology, faculty of pharmacy, university of uyo, uyo, nigeria emem ekpo umoh department of pharmacology and toxicology, faculty of pharmacy, university of uyo, uyo, nigeria

homalium letestui pellegr (flacourtiaceae) is used traditionally by the ibibios of southern nigeria to treat stomach ulcer, malaria and other inflammatory diseases and yorubas of western nigeria as an antidote. the hepatoprotective effect of the stem extract (200-600 mg/kg) was evaluated by the assay of liver function parameters, namely total and direct bilirubin, serum protein and albumin, tot...

Journal: :Clinical chemistry 1964
H R RONY M WEST H J ZIMMERMAN

Studies of serum glutathione reductase activity in thislaboratory prompted an attempt to demonstrate glutathione oxidase in the serum. The oxidation of reduced glutathione in the sera of patients with various diseases does not differ from normal sera. Preheating the serum and addition of cytochrome c does not effect the oxidizing capacity of the serum. The ability of serum to oxidize reduced gl...

Journal: :Bioscience, biotechnology, and biochemistry 2002
Motoko Awazuhara Hoyeun Kim Hiroaki Hayashi Mitsuo Chino Sang-Gu Kim Toru Fujiwara

The application of glutathione to immature soybean cotyledons reduced the accumulation of the beta subunit of beta-conglycinin, and increased the accumulation of most glycinins. Both reduced and oxidized forms of glutathione had these effects. The application of an inhibitor of glutathione synthesis, buthionine sulfoximine, increased accumulation of beta subunit. These results suggest that glut...

Journal: :The Journal of clinical investigation 1968
E E Rieber N S Kosower E R Jaffé

The ability of reduced nicotinamide adenine dinucleotide (NADH), generated through the activity of lactic acid dehydrogenase, to support the reduction of endogenous oxidized glutathione in intact human erythrocytes and in hemolysates was investigated. Rapid initial oxidation of endogenous reduced glutathione was effected with methyl phenylazoformate. Freshly obtained normal erythrocytes and ery...

Journal: :The Journal of biological chemistry 1989
Y Aniya M W Anders

The effect of enzymatically generated reduced oxygen metabolites on the activity of hepatic microsomal glutathione S-transferase activity was studied to explore possible physiological regulatory mechanisms of the enzyme. Noradrenaline and the microsomal cytochrome P-450-dependent monooxygenase system were used to generate reduced oxygen species. When noradrenaline (greater than 0.1 mM) was incu...

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