It has been well documented that shear forces effective above a certain magnitude under flow conditions causes damage in blood cells. This damage ranges from slight morphological alteration to the destruction of red blood cells (RBC). The hemolytic trauma to RBC can easily be detected by measuring free hemoglobin level in plasma, however there are no standardized protocols to quantitate subhemo...

a total of 1695 blood samples collected from ten ethnically distinct populations of iran (turks and kurds of rezaieh, lurs, aabolis, baluchis, turks and kurds of shrvan, zoroastrians, tehranis, and kermanis) were examined for six polymorphic red cell enzyme systems, namely red cell acid phosphatase (ap), adenylate kinase (ak), phosphoglucomutase (pgm1), esteraxe d (esd), adenosine deaminase (ad...

Erythroid ferritin was isolated from tadpole red blood cells, an unusually abundant source, with an iron content of 12%. The apoprotein was characterized by sedimentation equilibrium studies, sodium dodecyl sulfate gel electrophoresis, and by determination of amino acid composition. Tadpole red cell apoferritin has a molecular weight of 478,000, a subunit size of 19,600, and an amino acid compo...

Red blood cell (RBC) transfusion therapy is used in the clinical setting for a variety of indications, including patient resuscitation, augmentation of oxygen delivery, and to reverse or alleviate the symptoms of anemia [1–5]. Despite calls for a more conservative approach to blood transfusion as early as the late 1950s [6,7], the trend toward more cautious transfusion practices did not begin u...

Background: Red blood cells (RBCs) undergo biochemical and morphologic alterations during storage that are known as the storage lesions causing decreased RBC quality and are correlated with transfusion reactions in certain groups especially in infants and critically ill patients. Microvesicles (MVs) as one of storage lesions may be derived from various cell types and have key roles in several...