BACKGROUND Frequent outbreak of herpes labialis can affect quality of life by prodromes like burning, itching, and swelling. Topical applied preparations aim to shorten the duration of symptoms, inhibit the virus replication and/or accelerate the healing process. Local concentrated heat (LCH) can reduce burning, itching, or swelling of the skin by influence of mechano-heat sensitive afferent ne...

Methods Eighty-five (85) patients with JIA receiving etanercept in combination with MTX (etanercept/MTX) and 71 patients receiving MTX alone were enrolled at the Division of Rheumatology, Bambino Gesù Children’s Hospital, Rome, Italy. Incidence rates were calculated as the number of varicella cases, herpes zoster episodes and herpes labialis episodes per patient-years of follow-up (under specif...

Recurrent labial herpes simplex is a pathology of viral origin that is frequently observed in children. The signs and symptoms are uncomfortable and, in many cases, the efficacy of treatment is unproven. However, several studies have demonstrated good results from the use of low-level laser therapy (LLLT), primarily due to acceleration of the healing process and pain relief, which make it a pro...

Recurrent oral herpes labialis (ROHL) is a rather widespread oral ulcerative condition with an unclear etiology. The clinical characteristics of ROHL have been defined and therapies include systemic drugs and topical application of ointment to the lips. However, these approaches have not been rigorously evaluated. Persistent, painful ROHL was successfully treated with fucoidan in two patients. ...

DIEM: drug-induced erythema multiforme EM: erythema multiforme HAEM: herpes-associated erythema multiforme HSV: herpes simplex virus PCR: polymerase chain reaction INTRODUCTION Adalimumab is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor. We report a case of recurrent erythema multiforme (EM) recalcitrant to previous therapy that showed complete response t...

STATEMENT OF THE PROBLEM Herpes labialis infections are common and present a serious risk to the dental team. PURPOSE OF THE STUDY   The purpose is to make dentists aware of the risks involved with treatment of patients with active herpes labialis. In addition, evidence-based risk-management strategies are presented. METHODS AND MATERIALS The incidence and natural history of herpes simplex ...

Concurrent reactivation of herpes simplex and varicella zoster viruses is rare. Here, we describe the case of an elderly patient with herpes labialis and herpes zoster manifesting as a right-side facial eruption with vesicles and crusting. The loop-mediated isothermal amplification (LAMP) assay demonstrated the presence of both herpes simplex virus type 1 and varicella zoster virus in swab samp...