Objective(s): Diabetes mellitus causes impaired memory and cognitive functions. The hippocampus plays a key role in memory and learning. Curcumin attenuates diabetic nephropathy in vivo. Curcumin has shown a neurogenic effect and cognition-enhancing potential in aged rats. The aim of this study is to evaluate the possible protective role of curcumin on the histological and serologicalchanges of...

Objective: Despite the prevalence of obesity related liver disease in many countries, there is still no definitive pathway for prevention and treatment. The aim of this study was to determine the effect of combining resistance training and curcumin supplementation on liver enzyme in inactive obese and overweight Females. Materials and Methods: The study was done in a quasi-experimental trial. ...

Background and Objectives: Exercise and nutrition are two effective factors in controlling diabetes-induced metabolic disorders. The aim of this study was to assess effects of aloe vera and swimming training on lipid profile of the diabetic rats. Materials and Methods: In this experimental study, 72 diabetic rats were selected and divided into nine groups of eight rats, including 1) four weeks...

Introduction: This study aimed to show the potency of curcumin as an antiapoptotic agent that decreases the apoptotic index in the cochlea lateral wall in ototoxic rat models.   Materials and Methods: A total of 24 Rattus norvegicus were divided into eight groups: Group 1 (control group), Group 2 (gentamicin (+)), Group 3 (gentamicin + curcumin 20 mg/day), Group 4 (gentamicin + curcumin 40 ...

Curcumin and quercetin were evaluated in rats for their ability to modulate the carcinogenic activity of azoxymethane (AOM) in the colon and 7,12-dimethylbenz[a]anthracene (DMBA) in the mammary gland. In the AOM-induced colon cancer model, male Fischer 344 rats at 8 weeks of age started to receive either curcumin (8 and 16 g/kg) or quercetin (16.8 and 33.6 g/kg) in the diet and 1 week later, we...

introduction: obesity and visceral fat accumulation after menopause are associated with insulin resistance and cardiovascular diseases. we investigated the interactive effect of aerobic-resistance training and estrogen replacement therapy on visceral fat, omentin-1 and homa-ir in ovariectomized rats. materials and methods: fifty female wistar rats were ovariectomized (ovx) and divided into 5 gr...

Peripheral neuropathy is one of the major side effects of cisplatin; however, effective treatments are lacking. Curcumin is a polyphenol found in the root of Curcuma longa and has been shown neuroprotective against several neurological diseases. Nevertheless, its effects on cisplatin neuropathy remain unclear. This study aimed to clarify this issue by inducing neuropathy in the rats with intrap...