BACKGROUND Nevus spilus (NS) is a potential precursor of melanoma; the vast majority of cases reported in the literature were histologically classified as superficial spreading melanoma. OBJECTIVE To demonstrate the diagnostic value of reflectance confocal microscopy (RCM) in this subtype of congenital nevi. METHODS We report a case of a large congenital NS with equivocal clinical and dermo...

Reflectance confocal microscopy (RCM) is a novel application of scanning confocal microscopy that generates high spatiotemporal resolution images of the superficial layers of the skin in real time, performed by directly applying a confocal scanning head to the skin. Illumination is provided by infrared laser sources that generate low energy, high penetrance photons. Different structures provide...

We recently described an in vivo reflectance confocal microscopy (RCM) method and our aim was to evaluate a possible additive value of this type of analysis in the management of melanocytic lesions. In two referral centers (Sydney and Modena), lesions (203 nevi and 123 melanomas (MMs) with a median Breslow thickness of 0.54 mm) were excised on the basis of clinical suspicion (history, dermoscop...

OBJECTIVE To improve prebiopsy diagnostic accuracy and surgical management of pigmented appearing lesions on the lips, particularly melanoma, using in vivo reflectance confocal microscopy (RCM). STUDY DESIGN Prospective case series over a 12-month period between 2015 and 2016. The setting was two specialist dermatology referral centers with expertise in confocal microscopy. The study populati...

Reliability-Centred Maintenance in the Naval Air Systems Commands NAVAIR Programs. Air Canada.best practices and members experience in the application of them. This real world adobe illustrator cs2 pdf TECDOC describes the concept of Reliability Centred Maintenance RCM which is the.It is called Reliability-centered Maintenance, or RCM. If it is applied correctly, RCM transforms the relationship...

This paper presents the Random-Cluster Model (RCM), a stochastic time-variant, frequency-selective, propagation-based MIMO channel model that is directly parametrised from measurements. Using a fully automated algorithm, multipath clusters are identified from measurement data without user intervention. The cluster parameters are then used to define the propagation environment in the RCM. In thi...

BACKGROUND Actinic keratoses (AK) represent cutaneous carcinoma in situ and have previously been evaluated by reflectance confocal microscopy (RCM). Treatment of AK with imiquimod (IMIQ) 5% cream has been shown to 'highlight' subclinical lesions. OBJECTIVE The aim of this study was to test the applicability of RCM for noninvasive monitoring of actinic field cancerization and detection of subc...

Refiners today operate their equipment for prolonged periods without shutdown. This is primarily due to the increased pressures of the market resulting in extended shutdown-to-shutdown intervals. This places extreme demands on the reliability of the plant equipment. The traditional methods of reliability assurance, like Preventive Maintenance, Predictive Maintenance and Condition Based Maintena...

The incidence of melanoma has been on the rise for the last several decades, with a current US lifetime risk of developing melanoma estimated as 1 in every 60 individuals [1]. The key to preventing death from melanoma is the early detection of this cancer, at a stage where surgical excision is curative. However, in attempt to diagnose melanoma early, physicians are also removing many benign les...

Global and regional climate models are deterministic physical models which provide predictions of,amongst other things, future temperatures under a range of climate change scenarios. Predictions are available on grids with cells ranging from XX to YY (GCM) and XX to YY (RCM). The way in which these models are fitted means that they are often good at predicting changes in the mean temperature, b...