نتایج جستجو برای: rat corpus cavernosum

تعداد نتایج: 341323  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Allen Seftel

Significant impairment in endothelial-derived nitric oxide is present in the diabetic corpus cavernosum. RhoA/Rho-kinase may suppress endothelial nitric oxide synthase (eNOS). Here, we tested the hypothesis that RhoA/Rho-kinase contributes to diabetes-related erectile dysfunction and down-regulation of eNOS in the streptozotocin (STZ)-diabetic rat penis. Colocalization of Rho-kinase and eNOS pr...

2017
Woong Jin Bae Guan Qun Zhu Sae Woong Choi Hyun Cheol Jeong Fahad Bashraheel Su Jin Kim Seung Hwan Jeon Eun Bi Kwon Sae Woong Kim

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2017;6(S3) tau.amegroups.com (P<0.05). ESWT can promote proliferation of endothelial cells in corpus cavernosum. The result was significantly higher in the ESWT group than in the DMED group (P<0.05). ESWT can improve cell metabolism in vivo. The expression of mitochondrial membrane proteins is higher in the ESWT gro...

Journal: :Journal of andrology 2003
Somboon Leungwattanakij Trinity J Bivalacqua Mustafa F Usta Dae-Yul Yang Jae-Seog Hyun Hunter C Champion Asim B Abdel-Mageed Wayne J G Hellstrom

The etiologies of erectile dysfunction (ED) after nerve-sparing radical prostatectomy have not been clearly elucidated. The aim of this study was to evaluate the effects of cavernous nerve injury on cavernous fibrosis, and to consider measures to prevent irreversible damage to the cavernous tissues. Twenty male Sprague-Dawley rats constituted the study population. The animals were divided into ...

Journal: :BMC Urology 2006
Ahmed Shafik Ismail Ahmed Olfat El Sibai Ali A Shafik

BACKGROUND In a group of 22 patients with erectile dysfunction, vasculogenic, neurogenic, endocrinologic or psychogenic investigations failed to find a cause for their erectile dysfunction. The electro-cavernosograms of these patients recorded a diminished activity. We investigated the hypothesis that diminished corpus cavernosum electromyography activity was the cause of erectile dysfunction i...

2013
Rodrigo Araujo Fraga-Silva Fabiana Pereira Costa-Fraga Fabrizio Montecucco Younouss Faye Silvia Quintao Savergnini Sébastien Lenglet François Mach Sabine Steffens Nikolaos Stergiopulos Robson Augusto Souza dos Santos Rafaela Fernandes da Silva

Hypercholesterolemia is one of the most important risk factors for erectile dysfunction, mostly due to the impairment of oxidative stress and endothelial function in the penis. The cannabinoid system might regulate peripheral mechanisms of sexual function; however, its role is still poorly understood. We investigated the effects of CB2 activation on oxidative stress and fibrosis within the corp...

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