نتایج جستجو برای: ras al
تعداد نتایج: 471474 فیلتر نتایج به سال:
We previously reported that mouse NIH 3T3 cells transformed by transfection of activated human c-Ha-ras become apparently normal upon treatment with the antibiotic azatyrosine. The revertant cells maintain their normal phenotype during prolonged culture in the absence of azatyrosine, although activated p21ras is still expressed. The normal phenotype induced by azatyrosine could be due to activa...
Renal artery stenosis (RAS) is the most common cause of secondary hypertension. Preliminary data indicate that aspirin renography with hippurate may be more sensitive for detection RAS. In this study 20 patients with known or suspected RAS underwent aspirin renography (20 mg/kg orally 1 hour before injection of radiotracer) and captopril renography (50 mg orally) with 99mTc-DTPA. Renal an...
Background and purpose: Recurrent aphthous stomatitis (RAS) or oral aphthous are among the most common problems in adults. Stressful events could cause these ulcers. The purpose of this study was to determine the prevalence of recurrent aphthous stomatitis among students in Mazandaran University of Medical Sciences and its relationship with anxiety. Materials and methods: In this analytical cr...
Kinase inhibitors have ushered in the era of targeted therapy, but their utility to date is primarily limited to cancers bearing oncogenic kinase mutations. Two papers in this issue (Luo et al., 2009; Scholl et al., 2009) could change this landscape by uncovering kinase-specific vulnerabilities in tumors with RAS mutations.
The three mammalian ras proteins associated specifically with the plasma membrane and this is essential for their biological activity. Two signals encoded within the extreme COOH terminus of the proteins specify this cellular localization; a CAAX box in combination with either a polybasic domain (p21K-rasB) or a palmitoylation site (p21Ha-ras and p21N-ras). All members of the ras-like and rho-l...
Over the past 5 years or so, developmental geneticists studying the nematode and the fruit fly have provided many new insights into the signaling pathways linking cell surface receptor tyrosine kinases with nuclear transcription factors. A central component in this information transfer mechanism is the RAS protein, a low molecular weight GTP-binding protein that is a proto-oncogene product in m...
Background and Aims: The purpose of the present study was to review the studies regarding serological and salivary oxidant / antioxidant status in patients with recurrent aphthous stomatitis (RAS). Materials and Methods: The literature was searched using key words RAS, Antioxidants, Saliva, Hematinic (s) and Hematinic Acid in the last 10 years, particularly the recent 3 years (2010-2013). A...
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