Synthetic human pancreatic GH-releasing factor (1-44)NH2 (GRF) and acetylcholine (ACh) were shown to evoke a dose-related release of GH from cultured bovine pituitary cells with half-maximal effective doses of 0.3 and 500 nmol/l respectively. Concentrations of ACh (10 mumol/l) and GRF (25 nmol/l) which were shown to give near maximal responses when presented alone, produced highly synergistic r...

Adaptation of kinetics response when running on different surface has been commonly measured by the ground reaction force (GRF). GRF was extensively been used in studies related to surface characteristics such irregularity, incline and types. Since surface hardness effects on the ground reaction force response and the foot adaption is remain unclear, the present study was carried out to address...

Building on the weak CSR approach developed in a previous paper by Merlet, Nowak and Sergeev, we establish new bounds for periodicity threshold of powers tropical matrix. According to that approach, ultimate take form T=max(T_1,T_2), where T_1 is bound time after which expansion starts hold T_2 first term dominate. The established this make use cyclicity associated graph (tropical) factor rank ...

Whole-body inverse dynamics techniques have been recently proposed to assess the ground reaction forces and moments (GRF&M) only from motion data. Even though such techniques remove the dependency on force plate measurements, they are still bounded by the restrictions imposed by optical motion capture, i.e. the limited marker tracking volume, increased complexity, and requirement of a laborator...

Peak tibial acceleration (PTA) measured using accelerometers attached to the musculoskeletal system is considered the most effective method of quantifying impact shock magnitude as a result of footstrike during running. Ground Reaction Forces (GRFs) measured using force plates are also widely used to predict PTA. However it is not clear which is the most effective GRF variable to use. This has ...

Compensatory mechanisms in below-knee amputee gait are necessary due to the functional loss of the ankle muscles, especially at higher walking speeds when the mechanical energetic demands of walking are greater. The objective of this study was to examine amputee anterior/posterior (A/P) ground reaction force (GRF) impulses and joint kinetics across a wide range of steady-state walking speeds to...

Mechanography is an innovative method to evaluate lower-limb dynamic muscle function. This technique is generally performed on force platforms that measure only the vertical component of ground reaction force (GRF). The underlying assumption is that medio-lateral and antero-posterior forces do not contribute significantly to the GRF in jumping and rising tests. The goal of this study was to est...

Ground reaction forces and moments (GRF&M) are important measures used as input in biomechanical analysis to estimate joint kinetics, which often are used to infer information for many musculoskeletal diseases. Their assessment is conventionally achieved using laboratory-based equipment that cannot be applied in daily life monitoring. In this study, we propose a method to predict GRF&M ...

A peptide with high intrinsic activity for specifically stimulating the secretion of immunoreactive growth hormone (GH; somatotropin) has been characterized and reproduced by total synthesis. This peptide, human pancreatic growth hormone-releasing factor, 44-amino-acid form (hpGRF1-44-NH2), was isolated from a tumor localized in the pancreas of a patient with acromegaly. We report here the effe...