Cell cycle regulators are increasingly implicated in cell fate decisions, such as the acquisition or loss of pluripotency and self-renewal potential. The cell cycle mechanisms that regulate these cell fate decisions are largely unknown. We studied an S phase-dependent cell fate switch, in which murine early erythroid progenitors transition in vivo from a self-renewal state into a phase of activ...

(1) Background: Programmatic assessment optimizes the coaching, learning, and decision-making functions of assessment. It utilizes multiple data points, fit for purpose, which on their own guide but taken together form basis holistic decision making. While they are agreed principles, implementation varies according to context. (2) Context: The University Toronto MD program implemented programma...

The demand for computing and computing power is increasing at a rapid pace. With this demand, the ability to develop, enhance and maintain software is a top priority. Educating students to do competent work in software development, enhancement and maintenance has become a complex problem. Software engineering concepts are typically not introduced in beginning computer science courses. Students ...

In this paper, we discuss issues in designing undergraduate software engineering curricula in the Vietnam environment with regard to current circumstance and its potential changes. The field is still new in institutions, because traditionally they are much more concerned with the science of information processing rather than a systematic study of software engineering. Furthermore, rapid changes...

We show that superpolynomial decay of correlations (rapid mixing) is prevalent for a class of nonuniformly hyperbolic flows. These flows are the continuous time analogue of the class of nonuniformly hyperbolic maps for which Young proved exponential decay of correlations. The proof combines techniques of Dolgopyat and operator renewal theory. It follows from our results that planar periodic Lor...

When the times between renewals in a renewal process are not exponentially distributed, simulation can become a viable method of analysis. The renewal function is estimated through simulation for a renewal process simulation for a renewal process with gamma distributed renewal times and the shape parameter a > 1. Gamma random deviates will be generated by means of the so called Acceptance Rejec...

<em>This paper evaluates the effectiveness of sixth semester applied linguistics in English studies track preparing students for job market Morocco. A questionnaire survey was conducted with alumni program to assess extent which facilitated their employment, career advancement, and fulfillment professional expectations. The results revealed that involving development renewal is crucial. H...