RAP (Rapid Assessment Program) is a user-friendly and lightweight software implementation of a methodology for rapid, integrated policy analysis. Areas of application for RAP are virtually unlimited but have so far been mainly focussed on water resources management and scenario development in environmental engineering. Using an attractive visual interface, RAP takes its user through the steps i...

The interaction of a newly synthesized antitumor complex cis-dichloro-1,2-propylenediamine-N,N,N',N'-tetraacetato ruthenium (III) (RAP) with DNA was investigated in vitro through a number of techniques including comet assay, immunoprecipitation, and immunolocalization of certain nucleolar proteins (the upstream binding factor (UBF) and fibrillarin) involved in DNA transcription, rRNA processing...

The destruction of erythrocytes is one of the most frequently observed causes of severe malarial anemia. Recently, we showed that tagging normal erythrocytes and cells of erythroid precursors with rhoptry-derived proteins can trigger their destruction. In the present study, we used rhoptry-associated protein (RAP)-1 and RAP-3 gene-disruption mutant Plasmodium falciparum parasites and showed tha...

AIM To determine a novel chemotherapeutic concept for hormone receptor-negative and HER2-positive breast cancer, a high progression form of the disease for which treatment has been difficult. A combination therapy of 5-fluorouracil (5-FU) with rapamycin (Rap) was examined. MATERIALS AND METHODS The growth inhibitory effect of treatment was evaluated by an MTT assay and cellular signal/apoptot...

Rapid regular atrial pacing (RAP) produces changes in atrial function similar to those caused by atrial fibrillation in animal models. Left atrial appendage (LAA) function represents regional atrial function. The aim of our study was to investigate the influence of RAP on left atrial regional function and to evaluate the reversibility of changes after termination of pacing in a canine model. Ei...

Rap music has had a contentious relationship with the legal system, including censorship, regulation, and artists being arrested for lewd and profane performances. More recently, rap lyrics have been introduced by prosecutors to establish guilt in criminal trials. Some fear this form of artistic expression will be inappropriately interpreted as literal and threatening, perhaps because of stereo...

Megalin (gp330) is a member of the low-density lipoprotein receptor gene family. Like other members of the family, it is an endocytic receptor that binds a number of specific ligands. Megalin also binds the receptor-associated protein (RAP) that serves as an exocytic traffic chaperone and inhibits ligand binding to the receptor. To investigate the fate of megalin/RAP complexes, we bound RAP glu...

Immediate risk assessment and analysis are crucial in managing urban hazard events (UHEs). However, it is a challenge to develop an immediate risk assessment process (RAP) that can integrate distributed sensors and data to determine the uncertain model parameters of facilities, environments, and populations. To solve this problem, this paper proposes a RAP modeling method within a unified spati...

Babesia bovis merozoite apical membrane polypeptide Bv60 was found to be rhoptry associated by immuno-electron microscopy and was redesignated rhoptry-associated protein 1 (RAP-1). The N-terminal 300 amino acids of RAP-1 have a high level of sequence similarity to the same N-terminal region of p58, its homolog from Babesia bigemina. However, the interspecies conserved sequences did not include ...

A Road Accident Prevention (RAP) scheme based on Vehicular Backbone Network (VBN) structure is proposed in this paper for Vehicular Ad-hoc Network (VANET). The RAP scheme attempts to prevent vehicles from highway road traffic accidents and thereby reduces death and injury rates. Once the possibility of an emergency situation (i.e. an accident) is predicted in advance, instantly RAP initiates a ...