BACKGROUND The Cochrane Highly Sensitive Search Strategy (HSSS), which contains three phases, is widely used to identify Randomized Controlled Trials (RCTs) in MEDLINE. Lefebvre and Clarke suggest that reviewers might consider using four revisions of the HSSS. The objective of this study is to validate these four revisions: combining the free text terms volunteer, crossover, versus, and the Med...

Frobenius bimodules are connected with Frobenius algebras and extensions. For instance, a ring extension φ : R → S is a Frobenius extension if and only if RSS is a Frobenius bimodule [1]. Brzeziński and Gómez-Torrecillas studied in [4] certain properties of comatrix corings in relation to properties of bimodules. In particular they showed that the comatrix coring [6] induced by any Frobenius bi...

Many randomized controlled trials in which motivational interviewing (MI) is a key intervention make no provision for the assessment of treatment fidelity. This methodological shortcoming makes it impossible to distinguish between high- and low-quality MI interventions, and, consequently, to know whether MI provision has contributed to any intervention effects. This article makes some practical...

Characterizations of quasi-continuousmodules and continuousmodules are given. A non-trivial generalization of injectivity (distinct from p-injectivity) is considered.

In categories related to complete quasi-monoidal lattices, we investigate the relations among (L,♦)-(respectively, (L, )-,(L, )-) fuzzy quasi-uniform spaces, (L, ,∧)-fuzzy topological spaces and (L, ,∧)fuzzy interior spaces induced functions. Mathematics Subject Classification: 54A40, 08A72, 06D72

INTRODUCTION The standard methodologies for the design and conduction of randomized controlled trials (RCTs) are often difficult to be directly applied when older persons compose the target population (Pahor and Cesari, 2012). In fact, specific methodological adaptations are often required to guarantee the feasibility of the trial, ensure the participants’ adherence/compliance to the protocol, ...

Exergames have been suggested as an innovative approach to enhance physical activity in the elderly. The objective of this review was to determine the effectiveness of exergames on validated quantitative physical outcomes in healthy elderly individuals. We used Centre for Review and Disseminations guidance to conduct systematic reviews. Four electronic databases were searched. We included rando...

Most health care initiatives are evaluated using observational study designs in lieu of randomized controlled trials (RCT) due primarily to resource limitations. However, although observational studies are less expensive to implement and evaluate, they are also more problematic in determining causality than the RCT. This trade off is most apparent in the initial planning stage of program develo...

BACKGROUND Randomized controlled trials (RCTs) often have more than one primary outcome and frequently have secondary and harm outcomes. Comparison of outcomes between study arms is the primary focus of RCTs, but there are times when the relation between outcomes is important, such as determining whether an intermediate outcome and a clinical outcome have a strong association. We sought to dete...

INTRODUCTION In a previous review of randomized controlled trials (RCTs) on the pharmacotherapeutic management of aggression, it was shown that there is only weak evidence of effectiveness. In the present study we aim to determine comparability of patients included in these RCTs and patients of psychiatric long-stay wards. METHODS Exclusion criteria that were used in at least 20% of the RCTs ...