Objective(s): The aim of this study is to determine the effects of progesterone treatment on the survival of random skin flaps. Materials and Methods: McFarlane flaps were established and 40 male rats were randomly assigned to the progesterone-treated as the test group or normal saline-treated as the control group. Progesterone or normal saline (10 mg/kg) was administered intraperitoneally onc...

the distal third of the tibia, ankle and heel area is difficult to reconstruct. for small to medium size defects, local flaps are often an easier alternative than free flap. in lower limb surgery, the sural flap is based on this principle and this flap is becoming increasingly popular. the distally based superficial sural artery flap, first described as a distally based neuro skin flap by masqu...

IMPORTANCE Appropriate coverage of defects that expose tendon, joints, and/or neurovascular structures is necessary to preserve optimal hand function. Local, random-pattern flaps and skin grafts may be inadequate because of the hand's finite skin reservoir or the presence of a poorly vascularized and mobile wound bed. Described herein is a novel method of dorsal hand reconstruction. OBSERVATI...

INTRODUCTION Fournier's gangrene is a poly-microbial necrotizing fasciitis that involves the perineum and/or external genitalia. Urgent surgical debridement is well recognized as essential acute treatment yet unique challenges arise for plastic surgical reconstruction to obtain a complete functional recovery. This case describes a successful delayed pedicle flap repair based upon the anterior a...

BACKGROUND Vascular endothelial growth factor (VEGF) is a hormone-like molecule which has been shown to act on a specific receptor system and in this way to be the basic regulator of angiogenesis. The effect on the survival of a long random skin flap was examined by exogenous administration of this cytokine, at flap's recipient site. MATERIALS & METHODS A standard dorsal skin flap measuring 1...

Objective: To investigate the possible effects of laser diode 830nm counter to the action of nicotine on the viability of the skin flap in rats. Methods: 24 Wistar-albino rats were used, divided into 3 groups of 8: Group 1 subject to the surgical technique to obtain the random skin flap in cranial base, subcutaneous injection of nicotine of 2mg/Kg/day a week before and one week after surgery an...