نتایج جستجو برای: rallison syndrome

تعداد نتایج: 621917  

2012
Xia Xue Shao-Jian Li Muhammad Z. Ahmed Paul J. De Barro Shun-Xiang Ren Bao-Li Qiu

BACKGROUND The whitefly Bemisia tabaci is cryptic species complex composed of numerous species. Individual species from the complex harbor a diversity of bacterial endosymbionts including Wolbachia. However, while Wolbachia is known to have a number of different roles, its role in B. tabaci is unclear. Here, the antibiotic rifampicin is used to selectively eliminate Wolbachia from B. tabaci so ...

2010
GARY M. RODIN DENIS DANEMAN

IDDM and eating disorders are common conditions in young women. Whether a specific association exists between these two disorders remains controversial. Some studies have suggested an increased incidence of eating disorders in young women with IDDM, whereas others have not detected such an increase. These differences may be attributable, at least in part, to methodological issues in study desig...

Journal: :Physiological genomics 2004
Nora Klöting Barbara Wilke Ingrid Klöting

Congenic BB.SHR (D4Got41-Npy-Tacr1; BB.4S) rats develop an incomplete metabolic syndrome with obesity, hyperleptinemia, and dyslipidemia compared with their progenitor strain, the diabetes-prone BB/OK rat. To narrow down the underlying gene(s), two subcongenic BB.SHR rat lines, briefly termed BB.4Sa and BB.4Sb, were generated. Male BB.4S (n = 20), BB.4Sa (n = 24), and BB.4Sb (n = 26) were longi...

2015
Abdelhadi M. Habeb Asma Deeb Matthew Johnson Mohammed Abdullah Majidah Abdulrasoul Hussain Al-Awneh Mohammed S.F. Al-Maghamsi Fathiya Al-Murshedi Ramlah Al-Saif Siham Al-Sinani Dina Ramadan Hala Tfayli Sarah E. Flanagan Sian Ellard

BACKGROUND Wolcott-Rallison syndrome (WRS) is caused by recessive EIF2AK3 mutations and characterized by early-onset diabetes and skeletal dysplasia. Hepatic dysfunction has been reported in 60% of patients. AIMS To describe a cohort of WRS patients and discuss the pattern and management of their liver disease. METHODS Detailed phenotyping and direct sequencing of EIF2AK3 gene were conducte...

Journal: :Indian journal of biochemistry & biophysics 2014
Anubha Bajpai Neeraj Agarwal Satya P Gupta

A quantitative structure-activity relationship (QSAR) study was performed on a series of indole amide analogues reported by Dai et al. [Bioorg Med Chem Lett (2003), 13, 1897-1901] to act as histone deacetylase (HDAC) inhibitors. The multiple regression analysis (MRA) revealed a model showing the significant dependence of the activity on molar refractivity (MR) and global topological charge inde...

پایان نامه :دانشگاه آزاد اسلامی واحد علوم پزشکی تهران - دانشکده علوم پزشکی 1389

هدف: در این مطالعه به بررسی اثر تزریق کورتیکواسترویید در درمان infrapatellar fat pad syndrome در بیماران مراجعه کننده به درمانگاه ارتوپدی بیمارستان امیرالمومنین (ع) تهران در سال 1388 پرداختیم.روش مطالعه: این مطالعه به صورت یک بررسی مداخله ای (interventional) از نوع نیمه تجربی (quasi-experimental) انجام گردیده است. جامعه مورد بررسی شامل 60 نفر از افراد مبتلا به infrapatellar fat pad syndrome بود...

Journal: :Diabetes 2002
Anna Biason-Lauber Mariarosaria Lang-Muritano Tindara Vaccaro Eugen J Schoenle

Wolcott-Rallison syndrome (WRS) is an autosomal recessive disorder characterized by neonatal or early infancy type 1 diabetes, epiphyseal dysplasia, and growth retardation. Mutations in the EIF2AK3 gene, encoding the eukaryotic initiation factor 2alpha-kinase 3 (EIF2AK3), have been found in WRS patients. Here we describe a girl who came to our attention at 2 months of age with severe hypertonic...

Journal: :Endocrinology 2003
Yulin Li Kaori Iida Jeff O'Neil Peichuan Zhang Sheng'ai Li Ami Frank Aryn Gabai Frank Zambito Shun-Hsin Liang Clifford J Rosen Douglas R Cavener

Humans afflicted with the Wolcott-Rallison syndrome and mice deficient for PERK (pancreatic endoplasmic reticulum eIF2alpha kinase) show severe postnatal growth retardation. In mice, growth retardation in Perk-/- mutants is manifested within the first few days of neonatal development. Growth parameters of Perk-/- mice, including comparison of body weight to length and organ weights, are consist...

پایان نامه :دانشگاه آزاد اسلامی واحد علوم پزشکی تهران - دانشکده پزشکی 1390

مقدمه : impingement syndrome یکی از بیماریهای شایع است که با درد شانه ومحدودیت حرکت در مفصل شانه همراه می باشد. با توجه به اهمیت این موضوع و لزوم دستیابی به روشی مطمئن جهت درمان مبتلایان به این بیماری، در این مطالعه به بررسی میزان اثربخشی استفاده از glyceril trinitrate بصورت موضعی در درمان مبتلایان بهimpingement syndrome پرداختیم. مواد و روشها: در این مطالعه که از نوع مداخله ای-تحلیلی میباشد60...

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