Deepak Raghavan, MD, Jerrold Boxerman, MD, PhD, Suriya Jeyapalan, MD, MPH, and Jeffrey Rogg, MD  a 64 year old Male was referred To The neurosurgiCal serviCe at Rhode Island Hospital for evaluation of a left frontal mass. Given proximity of the lesion to eloquent cortex, resection was not performed and a histopathologic diagnosis of grade III anaplastic oligoastrocytoma was made through biopsy...

We report a case of radiation necrosis in an unusual location, the pons, in a patient who had received chemoradiation for nasopharyngeal carcinoma (NPC) over one year prior to presentation. This patient presented with subacute onset of ataxic hemiparesis and slurred speech. Initial magnetic resonance imaging (MRI) studies showed two 1-2 cm peripherally contrast-enhancing lesions in the pons wit...

INTRODUCTION High grade gliomas are the most common primary malignant brain tumours. Treatment with chemoradiation and adjuvant chemotherapy with Temozolomide may prolong survival but some patients develop complications during or soon after therapy due to radiation necrosis, oedema or tumour progression. PATIENTS We report the use of Bevacizumab in four patients with newly diagnosed high grad...

Three cases of pseudomonas endophthalmitis associated with scleral necrosis 3 to 10 years after pterygium excision and beta irradiation are described. The value of prophylactic repair of radiation-induced scleral necrosis and early aggressive management of pseudomonas endophthalmitis are emphasized.

Background: Current imaging-based discrimination between radiation necrosis versus recurrent glioblastoma contrast-enhancing lesions remains imprecise but is paramount for prognostic and therapeutic evaluation. We examined whether patients with exhibit distinct patterns of blood oxygenation-level dependent fMRI cerebrovascular reactivity (BOLD-CVR) as the first step to better distinguishing fro...