A purification and fractionation process of the edible flowers Tibouchina mollis urvilleana followed by first attempt to anthocyanin flavonol characterisation identification UHPLC-DAD-ESI-MS were developed. T. exhibited a higher monomeric content, mainly due presence 3-O-(6′-p-coumaroyl)-glucoside derivatives malvidin petunidin. Quercetin-3-O-hexoside was major identified in urvilleana, lack my...

Flavonoids are rich in Juglans regia L. leaves. They have potent antioxidant properties, which have been related to regulating immune function and enhancing anticancer activity. Herein, qualitative and quantitative determination of flavonoids from J. regia leaves was carried out using high performance liquid chromatography coupled with tandem mass spectrometry with electrospray ionization and n...

Oxidative stress has been implicated in the pathogenesis of many kinds of neurodegenerative disorders, particularly Parkinson's disease. Quercetin is a bioflavonoid found ubiquitously in fruits and vegetables, and has antioxidative activity. However, the underlying mechanism of the antioxidative effect of quercetin in neurodegenerative diseases has not been well explored. Here, we investigated ...

The bioactive ethyl acetate and N-butanol soluble parts of an ethan leaves was subjected to column chromatography over silica gel G (60 120 flavonoid rich fraction over sephadex LH-20 eluted with methanol led to th identified as quercetin 3-O-α-arabinoside (I), quercetin(II) and quercetin 3elucidated by H and C-NMR data and are reported here for the first time

One new and six known flavone glycosides were isolated from the MeOH extract of Melilotus neapolitana Ten. The new compound, identified as 7-O-beta-D-glucopyranosyloxy-4',5-dihydroxy-3-[O-alpha-L-rhamnopyranosyl-(1-->6)-3-O-beta-D-glucopyranosyloxy]flavone (1) by 1D and 2D NMR techniques and mass spectra, was isolated along with kaempferol-3-O-rutinoside (2), kaempferol-3-O-glucoside (3), rutin...

A phytochemical investigation of Ficus virens leaves led to isolation of six flavonoids (1–6). On the basis of 2D and/or 1D NMR, and mass data, together with the comparison with the literature values, the flavonoids were identified as quercetin (1), quercetin-3-O-α-D-arabinopyranoside (2), quercetin-3-O-β-Dgalactopyranoside (3), kaempferol-3-O-α-D-arabinopyranoside (4), kaempferol-3-O-β-Dgalact...

A new flavonol galactopyranoside, myricetin 3-O-(2'',3''-digalloyl)-β-D-galactopyranoide (1), and 23 known constituents, including myricetin 3-O-(2''-galloyl)-β-D-galactopyranoide (2), myricitrin (3), myricetin (4), quercetin 3-O-(2'', 3''-digalloyl)-β-D-galactopyranoide (5), quercetin 3-O-(2''-galloyl)-β-D-galactopyranoide (6), hyperin (7), isoquercetrin (8), quercetin (9), kaempferol (10), ap...

The reaction of the flavonol 3,7,3', 4'-tetra-O-methylquercetin (1) and of the isoflavone 7,4'-di-O-methylgenistein (2) with alkaline iodine in methanol afforded four new iodine derivatives: 8-iodo-5-hydroxy-3,7,3', 4'-tetramethoxy- flavone (1a) and 6-iodo-5-hydroxy-3,7,3', 4'-tetramethoxyflavone (1b) from 1; 2 afforded a mixture of two compounds, identified as a racemic mixture of (+/-)-trans-...

Recent experimental data point to an interaction of dietary flavonol monoglucosides with the intestinal Na-dependent glucose transporter 1 (SGLT1). To investigate this interaction in more detail, we performed experiments with SGLT1-containing brush-border-membrane vesicles (BBMV) from pig jejunum. The flavonol quercetin-3-O-glucoside (Q3G) concentration-dependently inhibited Na-dependent uptake...

Byrsonima basiloba A. Juss. species is a native arboreal type from the Brazilian "cerrado" (tropical American savanna), and the local population uses it to treat diseases, such as diarrhea and gastric ulcer. It belongs to the Malpighiaceae family, and it is commonly known as "murici." Considering the popular use of B. basiloba derivatives and the lack of pharmacological potential studies regard...