Phenols are important industrial chemicals, and because they can be volatile, also appear as air pollutants. We examined the potential of tyrosinase to react with the volatile phenol p-cresol. Three lines of evidence support the conclusion that volatile phenols react with tyrosinase and are coupled (i.e., chemisorbed) onto chitosan films. First, phenol-trapping studies indicated that p-cresol c...

Introduction: Colon carcinoma is one of the most common form of cancer that affects the health and lives of people. 5-Fluorouracil (5-Fu) has become useful as synergistically therapy with other antitumor agents in a colon cancer therapy. Short half-life, wide distribution and different side effects of 5-Fu limit its medical applicability. In this study, we have investigated the...

Chitosan with excellent biodegradable and biocompatible characteristics has received attention as an oral drug delivery vehicle for controlled-release formulations. In this study an enteric-coated capsule containing theophylline-chitosan beads based on 23 factorial designs was prepared as a colon drug delivery system. The theophylline-chitosan gel beads were formulated by adding the drug-contai...

In this study, by taking the advantage of both inorganic ZnO nanoparticles and the organic material chitosan as a composite seed layer, we have fabricated well-aligned ZnO nanorods on a gold-coated glass substrate using the hydrothermal growth method. The ZnO nanoparticles were characterized by the Raman spectroscopic techniques, which showed the nanocrystalline phase of the ZnO nanoparticles. ...

Polyelectrolyte-coated nanoparticles or microparticles interact with bioactive molecules (peptides, proteins or nucleic acids) and have been proposed as delivery systems for these molecules. However, the mechanism of adsorption of polyelectrolyte onto particles remains unsolved. In this study, cationic poly(lactide-co-glycolide) (PLGA) nanoparticles were fabricated by adsorption of various conc...

introduction: oral delivery is the most favorable route for insulin administration. the aim of this study was to generate new chitosan coated insulin nanoliposomes and then to assess the physiological efficacy of these nanoliposomes after oral administration in diabetic rabbits. methods: nanoliposomes with negative surface charge encapsulating insulin were prepared by reverse phase evaporation ...

Triticum aestivum L. and Zea maize L. are both sensitive to salinity stress which is a major problem faced by farmers today. In the present study, the effect of chitosan, a biologic elicitor under salinity stress was examined on growth parameters and biochemical markers in maize and wheat s...

application of edible coatings to enhance storage life of fresh fruit has recently been under considerable attention. this experiment was conducted in order to explore the effect of chitosan coating and storage temperature on the postharvest life of pomegranate (punica granatum l.) fruit. therefore, pomegranate fruits ‘rabbab-e-neyriz’ were dipped in 0, 1 and 2% aqueous chitosan solutions, air ...

Four hydrophilic polymers in the form of beads - chitosan, alginate, alginate/polyvinyl alcohol (PVA), and chitosan-coated alginate - were used as supports for lipase immobilisation. Hydrogel beads were characterised by bead-size-distribution estimation, surface morphology studies, and polymer interactions assessment. Matrix performances - loading efficiency, immobilisation yield, enzyme activi...