BACKGROUND B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) is thought to be an indolent disease, with a good prognosis following various forms of treatment. Little, however, is known about the rate and pattern of relapse following successful treatment. PATIENTS AND METHODS We have analyzed time to and pattern of relapse in patients with MALT lymphoma, along with inves...

We report the first dry-reagent, disposable, dipstick test for molecular screening of seven chromosomal translocations associated with acute and chronic leukemia. The dipstick assay offers about 10 times higher detectability than agarose gel electrophoresis and, contrary to electrophoresis, allows confirmation of the sequence of the polymerase chain reaction (PCR) product by hybridization withi...

Nowadays, it is believed that the main role in the development of gastric mucosa-associated lymphoid tissue (MALT) lymphoma plays Helicobacter pylori infection. This world-wide distributed bacteria is in charge of most cases of not only upper gastrointestinal tract disorders but also some of extragastric problems. Constant stimulation of the immune system causes a B-lymphocytes proliferation, w...

between t(11;18)(q21;q21) of gastric MALT lymphomas and CagA strains of H pylori. Furthermore, they show that t(11;18)(q21; q21)-positive MZLs of MALT in other sites do occur, however, in a nonrandom fashion (ie, 38% and 24% in the lung and stomach, respectively, versus 1% in the salivary gland). Ye et al’s proposal that the missing link might be chromosomal damage caused by oxidative stress in...

Abstract Mucosa-associated lymphoid tissue (MALT) lymphoma is generally associated with chronic antigen stimulation: auto-antigens or of microbial origin. Only one study suggested association between Achromobacter xylosoxidans and pulmonary MALT lymphoma. We aimed to investigate the presence virus any infectious agents in by using metagenomic next-generation sequencing (mNGS). All lung samples ...

Monoclonal antibody 7.1, which recognizes the chondroitin sulfate proteoglycan molecule NG2, was used to screen prospectively blast cells from 104 consecutive children at initial presentation with acute lymphoblastic leukemia (ALL). Reactivity with this antibody was found in 9 cases (8.6’701, of whom5hadat(4;11)(q21;q23)and4hadat(11;19)(p13;q23). None of the NG2cases had either translocation. S...