نتایج جستجو برای: pyrimidinones

تعداد نتایج: 113  

Journal: :Scientific Bulletin of the Uzhhorod University. Series «Chemistry» 2020

2014
A. C. H. Pape Maartje M. C. Bastings Roxanne E. Kieltyka Hans M. Wyss Ilja K. Voets E. W. Meijer Patricia Y. W. Dankers

Hydrogels and, in particular, supramolecular hydrogels show promising properties for application in regenerative medicine because of their ability to adapt to the natural environment these materials are brought into. However, only few studies focus on the structure-property relationships in supramolecular hydrogels. Here, we study in detail both the structure and the mechanical properties of su...

In this research, Cu-phthalocyanine coated hybrid magnetic nanoparticles have been prepared in a simple method and evaluated as an efficient catalyst in the preparation of mono- and bis-pyrano[2,3-d]pyrimidinones and mono- and bis-2-amino-4H-pyrans from the condensation reaction of 1,3-dimethylbarbituric acid or 4-hydroxycumarin with malononitrile and mono- and bis-aldehydes under ultrasoni...

2015
Eduard Rais Ulrich Flörke René Wilhelm

The unit cell of the title complex, [CoBr2(C18H20N2O)2], contains 1.5 formula units per asymmetric unit with one mol-ecule sitting on a general site and a second one halved by a crystallographic twofold rotation axis passing through the Co(II) cation. Both Co(II) atoms are coordinated in a distorted tetra-hedral manner by two Br(-) ligands and two O atoms of the pyrimidinone (OPyr) groups. The ...

Journal: :Journal of medicinal chemistry 2007
Ariane Jansma Qiong Zhang Bing Li Qiang Ding Tetsuo Uno Badry Bursulaya Yi Liu Pascal Furet Nathanael S Gray Bernhard H Geierstanger

2D 1H-15N HMBC NMR acquired at natural abundance and DMSO titration monitored by 1D 1H NMR verified the existence of an intramolecular hydrogen bond that was designed to mimic the pyrimidinone ring of a class of kinase inhibitors. A scalar coupling across the hydrogen bond was detected in organic and aqueous solvent, suggesting a simple and general approach for testing the propensity of intramo...

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