نتایج جستجو برای: pyridazinone
تعداد نتایج: 198 فیلتر نتایج به سال:
The effects o f three differently substituted pyridazinone herbicides were studied on the lipid content, fatty acid composition o f glycerolipids, fatty acid synthesizing capacity and ultrastruc ture of chloroplasts after 72 h o f greening o f etiolated barley leaves. SAN 9789 caused a nearly threefold increase in the total fatty acid content o f chloroplasts, and this increase was accom pan...
The echinocandins are a class of semisynthetic natural products that target β-1,3-glucan synthase (GS). Their proven clinical efficacy combined with minimal safety issues has made the echinocandins an important asset in the management of fungal infection in a variety of patient populations. However, the echinocandins are delivered only parenterally. A screen for antifungal bioactivities combine...
The effect of a cardiotonic agent, MCI-154, 6-[4-(4’-pyridylamino)phenyl]-4,5-dihydro-3(2H)-pyridazinone hydrochloride trihydrate, is a Ca2+ sensitizer on the contractile properties and adenosine triphosphatase ATPase activity on skeletal muscle fibers. As in cardiac m uscle, MCI-154 potentiated isometric tension and improved isometric tension cost at full Ca 2+ activation. However, MCI-154 dec...
Repurposing strategies on pyridazinone-based series by pharmacophore- and structure-driven screening
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