In the title salt, C(11)H(14)N(3)O(+)·C(7)H(5)O(3) (-), the phenyl ring of the cation is oriented at an angle of 67.0 (1)° with respect to the five-membered pyrazolone ring. The carboxyl-ate plane of the anion is twisted out from the plane of the aromatic ring at an angle of 13.7 (3)°. In the crystal, the cations form hydrogen-bonded dimers with an R(2) (2)(10) ring motif. The salicylate anion ...

In the title compound, C(26)H(23)N(5)O(2)S, an intra-molecular N-H⋯O inter-action generates an S(6) ring. The essentially planar S(6) and pyrazole rings [maximum deviations = -0.0270 (14) and 0.0195 (15) Å, respectively] are nearly coplanar, making a dihedral angle of 3.94 (6)°. The S(6) ring makes dihedral angles of 23.79 (6), 78.53 (6) and 67.91 (6)° with the pyrazolone ring, the pyrazole rin...

An efficient and convenient synthesis of pyrrolidinones and pyridinones utilizing enamino esters as starting material has been described. The structures of the compounds obtained were confirmed by spectral and elemental analyses.

In the title compound, C(24)H(20)BrN(3)O(4)S, the central benzene ring makes dihedral angles of 24.55 (8), 49.52 (12) and 59.65 (7)°, respectively, with the pyrazolone ring, the bromo-benzene ring and the terminal phenyl ring. The packing is stabilized by weak non-classical inter-molecular C-H⋯O=C hydrogen bonds that form inversion-related dimers.

Fifty drugs, applied in the therapy of internal diseases, were investigated for their effect on the clinical chemical determination of serum glucose by the automated GOD-Perid method. The results showed a statistically significant depression of the reported glucose value, by 7 drugs containing the pyrazolone group and its derivatives (Baralgin, Butazolidine, Analgin, Novalgetol, Analgocain, Irg...