Pseudomonas aeruginosa is a waterborne ubiquitous opportunistic pathogen that can be fatal for immunocompromised patients. Here, we report the use of paper-based screen-printed sensors electrochemical detection P. in water sources only 14 s. identifiable by its unique biomarker pyocyanin, which redox-active and therefore suitable direct without sample pretreatment. The method was applied to det...

This study was aimed to examine and detect the total flavonoid presence from crude extract use in phytochemical test HPLC device, detecting on both by UV-spectrophotometer. The objective of this for inhibition pyocyanin pigment that produce pseudomonas aeruginosa Marticaria chamomilla extract. extraction chamomile accomplished methanol 80%, where different concentrations dilutions used as anti-...

Pseudomonas aeruginosa PA14 cells resistant to the novel antimicrobial gallium nitrate (Ga) were developed using transposon mutagenesis and by selecting spontaneous mutants. The mutants showing the highest growth in the presence of Ga were selected for further characterization. These mutants showed 4- to 12-fold higher Ga minimal inhibitory growth concentrations and a greater than 8-fold increa...

Background: Due to its extensive arsenal of virulence factors and inherent resistance to antibiotics, Pseudomonas aeruginosa is a threat particularly in immunocompromised patients. Considering the central role of quorum sensing in the production of virulence factors, inhibition of bacterial communication mechanism constitute an opportunity to attenuate pathogenicity of bacteria resistant to ava...

Pyocyanin production by Pseudomonas aeruginosa can be monitored using hyperspectral imaging and square wave voltammetry, with electrochemical impedance spectroscopy offering new avenues for low-cost sensing approaches to biofilm characterisation.

BACKGROUND Quorum sensing is the key regulator of virulence factors of Pseudomonas aeruginosa such as biofilm formation, motility, productions of proteases, hemolysin, pyocyanin, and toxins. The aim of this study was to explore the effect of the extracts from some medicinal plants on quorum sensing and related virulence factors of P. aeruginosa. MATERIAL AND METHODS Quorum sensing inhibitory ...

Pathogenic microbes employ a variety of methods to overcome host defenses, including the production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa, a Gram-negative bacterium, is a pathogen of a diverse variety of hosts including mammals and the nematode Caenorhabditis elegans. In this study, we identify three small molecules in the phenazine class that are prod...

Pseudomonas aeruginosa is a human pathogen associated with a variety of life-threatening nosocomial infections. This organism produces a range of virulence factors which actively cause damage to host tissues. One such virulence factor is pyocyanin, known to play a crucial role in the pathogenesis of P. aeruginosa infections. Previous studies had identified a novel compound capable of strongly i...

Pseudomonads are well known for their degradative abilities and play an important role in the environmental cleanup and they are well known for their opportunistic pathogenic properties. The characteristic feature of Pseudomonas aeruginosa is the production of soluble pigments like Pyocyanin, which is an secondary metabolite that is produced in both solid and liquid culture media. Pyocyanin iso...