Currently, much information is provided regarding the presence and the roles in tissue regeneration of stem cell niches residing in post-natal dental pulp. So far, three types of adult stem cells have been isolated from dental pulp. Correct evaluation of these cells is important in order to determine their potential use in clinical fields. The present study aims to review the origins and immuno...

regenerative endodontic procedure is introduced as a biologically based treatment for immature teeth with pulp necrosis. successful clinical and radiographic outcomes following regenerative procedures have been reported in landmark case reports. retrospective studies have shown that this conservative treatment allows for continued root development and increases success and survival rate of the ...

The success of pulpotomy of young permanent teeth depends on the proper selection of dressing materials. This study aimed to evaluate the histological and histomorphometric response of dentin-pulp complex to the enamel matrix derivative (Emdogain(®) gel) compared to that of calcium hydroxide when used as a pulp dressing in immature young permanent dogs' teeth. Dentin-like tissues bridging the f...

Derived from neural crests, the mature pulp is due to the proliferation and condensation of apical cells implicated in root lengthening. Adult cells are bound together by intercellular junctions (desmosomes and gap junctions), forming a network. They are further transported to the crown. Root lengthening is associated to tooth eruption and to vertical sliding. Composed by type I and III collage...

Dental pulp has been identified as a novel and promising stem cell source. The following systematic review presents and summarises in vivo studies that have used stem cells from the dental pulp of permanent and deciduous teeth to repair or regenerate non-dental tissues. An electronic customised search was performed using 4 different databases (Entrez PubMed, Cab Abstracts, Scopus and Web of Sci...

INTRODUCTION The purpose of this study was to evaluate the effectiveness of autologous platelet concentrates (APCs) in promoting pulp and dentin regeneration in animal models. METHODS An electronic search was performed on MEDLINE, Embase, Scopus, SciELO, LILACS, and CENTRAL. Animal studies using APC as a root filling material after pulpectomy in mature or immature teeth were included. Article...