background: following pulmonary aspiration of gastric contents, a variety of conditions occurs ranging from the acute inflammatory response (aspiration pneumonitis) to an infectious process (aspiration pneumonia). they cause due to the failure of protecting mechanism of airway patency following poisoning toxicity. methods: patients with acute drug poisoning for assessment of aspiration-induced ...

Sulphasalazine prescribing is on the increase. Pulmonary toxicity and blood dyscrasias are rare side-effects. Numerous case reports have been published implicating sulphasalazine in pulmonary toxicity. The authors searched the literature for cases of sulphasalazine induced lung toxicity and the 50 cases identified are discussed here. All published case reports/letters referring to sulphasalazin...

Oxygen (O2) toxicity may result from exposure to partial pressures of O2 above 0.6ATA. Potential toxic exposure for divers occurs during the treatment of dysbarism. In the recompression chamber, PO2 may range from 0.9ATA to 3.3ATA depending upon the treatment table employed. This retrospective study examines the nature and incidence of O2 toxicity in 998 patients who underwent recompression tre...

OBJECTIVE We reviewed studies on pulmonary, reproductive, and developmental toxicity caused by carbon nanotubes (CNTs). In paricular, we analyzed how CNT exposure affects the several processes of pulmonary toxicity, including inflammation, injury, fibrosis, and pulmonary tumors. METHODS In pulmonary toxicity, there are various processes, including inflammation, injury, fibrosis, respiratory t...

Correspondence t Davidson. The increased use of malaria prophylaxis has led to more reports of drug induced toxicity. Hepatic, renal, skin, and bone marrow effects are well recognised. Five cases of pulmonary toxicity and systemic illness after the use of pyrimethamine-sulfadoxine (Fansidar) have been reported.'-' In two of these reports rapidly progressive respiratory failure developed and ope...

We report a case of a female admitted to the emergency department with fever and severe type I acute respiratory failure. After detailed examination, all other potential causes were excluded and the patient was diagnosed with nitrofurantoin-induced acute pulmonary toxicity.

Gemcitabine (2’,2’-difluoro-s’-deoxycytidine; Gemzar, Eli Lilly, Indianapolis, IN, USA), a pyrimidine nucleoside analogue similar to cytarabine, inhibits DNA synthesis both by halting DNA replication through the incorporation of its active form into DNA and also by inhibiting ribonucleotide reductase and deoxycytidine monophosphate deaminase [1, 2]. It is administered as a prodrug that becomes ...