It is well known that there is a very high mortality in children with ventricular septal defect, who develop heart failure in early infancy (Marquis, 1950; Boesen and Vendel, 1955). Morgan, Griffiths, and Blumenthal (1960) reviewed 125 children up to 14 years of age with ventricular septal defect. Of these, 17 developed heart failure in the first six months of life, 10 dying before their first ...

AIMS An important pathogenic mechanism in the development of idiopathic pulmonary arterial hypertension is hypothesized to be a cancer-like cellular proliferation independent of haemodynamics. However, because the vascular lesions are inseparably coupled with haemodynamic stress, the fate of the lesions is unknown when haemodynamic stress is eliminated. METHODS AND RESULTS We applied left pul...

Between January 1974 and November 1980, 13 symptomatic infants under 1 year of age with persistent truncus arteriosus type I or II underwent surgery. Pulmonary artery banding was performed in 10 cases, with five deaths. Among the survivors, one developed severe pulmonary vascular disease and only two underwent late intracardiac repair. Primary total correction was performed in three infants and...

DOI: 10.5935/abc.20130156 Clinical Data: After surgical correction of the transposition of the great arteries associated with other defects and heart failure, beginning with termino-terminal coartectomy and pulmonary artery banding at three months (weight = 3800 g) and use of the Jatene technique with the closing off of interventricular communication, and pulmonary banding at ten months (weight...

Abstract Background Pulmonary hypertension is a significant risk factor in patients undergoing surgery. The combined effects of general anaesthesia and positive pressure ventilation can aggravate this condition cause increased pulmonary blood pressures, reduced systemic pressures ventricular contractility. Although perioperative use inotropic support or vasopressors almost mandatory for these p...

Twenty seven months after pulmonary artery banding a boy aged two and a half developed rapidly progressive cyanosis. A periarterial abscess was found at the site of the band. Repair of the pulmonary artery and closure of the ventricular septal defect were complicated by profoundly low cardiac output and prolonged dependence on a ventilator. This near fatal complication would have been avoided b...