Council Decision 2005/387/JHA defines a new psychoactive substance as ‘a new narcotic drug or a new psychotropic drug in pure form or in a preparation, that has not been scheduled under the 1961 United Nations Single Convention on Narcotic Drugs, and that may pose a threat to public health comparable to the substances listed in Schedule I, II or IV (new narcotic drug) or under the 1971 United N...

Novel psychoactive substances are newly used designer drugs ("internet drugs", "research chemicals", "legal highs") potentially posing similar health risks to classic illicit substances. Chemically, many novel psychoactive substances can be classified as phenethylamines, amphetamines, synthetic cathinones, piperazines, pipradrols/piperidines, aminoindanes benzofurans, and tryptamines. Pharmacol...

Introduction. Destruction is one of the stages circulation medicines. Special importance attached to this stage in relation drugs related narcotic and psychotropic substances. The activities pharmacy medical organizations turnover these funds are strictly regulated. Aim. purpose study was procedure for destruction substances included Lists II III List, as a medicines, identify trends appointmen...

Introduction: Psychiatric disorders have become a global problem that leads millions of people to use psychotropic medications, especially benzodiazepines. The effects these substances are widely known regarding tolerance and chemical dependence, however, from epigenetics perspective, there still little known.
 Objective: To evaluate the association between drug use, NR3C1 gene methylation...

Various instrument types and LC-MS approaches have been explored in an attempt to develop a comprehensive analysis method for detecting and definitely identifying as many compounds as possible in a single run. However, everyday analyses often require the detection of a defined set of substances (for example, hypnotics in cases of drugfacilitated assault (DFA). The aim of this project was to dev...

Background and Objectives: The expanding field of psychopharmacology is constantly seeking new and improved drugs to treat psychiatric disorders. Although psychotropic drugs have had a remarkable impact in psychiatry, their utilization, effectiveness, and side effects in the in clinical practice need continuous study. The present study was thus designed to analyze the pattern of psychotropic dr...

Using a standard epidemiological survey instrument for psychoactive drug use, 215 medical students in three classes were studied. One third of all students reported non-medical drug use. The substances ever used were: betel nut 13%, smokeless tobacco 3%, cigarettes 12%, alcohol 12.5%, cannabis 0.9% and benzodiazepines 3.7%. Last month use was reported for four substances and daily use was repor...