there is a general consensus that climate change has impact on the intensity and frequency of rainfall events. however, very little research is available about the changes in short term rainfall extremes. the focus of this paper has been on the change in annual and monthly rainfall extremes in ontario. the results indicate a greater variability (increase and decrease) among stations for shorter...

retrotransposons (rtns) constitute informative molecular markers for plant species because of their ability to integrate into a multitude of loci throughout the genome and thereby generate insertional polymorphisms between individuals. in the present study, rtn-based molecular markers, irap (inter-retrotransposon amplified polymorphism) and remap (retrotransposon-microsatellite amplified polymo...

designing breeding programs for winter rapeseed (brassica napus l.) cultivars with improved seed and oil yields requires information about the genetic variability of traits. in this study, 28 winter rapeseed cultivars were evaluated for genetic variation and relationships between 11 agro-morphological characters during 2010 and 2011. cultivars and cultivar × year interaction showed significant ...

Protein flexibility is often implied in binding with different partners and is essential for protein function. The growing number of macromolecular structures in the Protein Data Bank entries and their redundancy has become a major source of structural knowledge of the protein universe. The analysis of structural variability through available redundant structures of a target, called multiple ta...

Olmesartan medoxomil (OM) is a prodrug-type angiotensin II type 1 receptor antagonist. OM is rapidly converted into its active metabolite olmesartan by multiple hydrolases in humans, and we recently identified carboxymethylenebutenolidase homolog (CMBL) as one of the OM bioactivating hydrolases. In the present study, we further investigated the interindividual variability of mRNA and protein ex...

Olmesartan medoxomil (OM) is a prodrug-type angiotensin II type 1 receptor antagonist. OM is rapidly converted into its active metabolite olmesartan by multiple hydrolases in humans, and we recently identified carboxymethylenebutenolidase homolog (CMBL) as one of the OM bioactivating hydrolases. In the present study, we further investigated the interindividual variability of mRNA and protein ex...