background: the mechanisms of virulence and species differences of leishmania parasites are under the influence of gene expression regulations at posttranscriptional stages. in iran, l. major and l. tropica are known as principal agents of cutaneous leishmaniasis, while l. infantum causes visceral leishmaniasis. methods: as a preliminary study, we compared the proteome mapping of the above thre...

Polysorbate is widely used to maintain stability of biotherapeutic proteins in pharmaceutical formulation development. Degradation polysorbate can lead particle formation drug products, which a major quality concern and potential patient risk factor. Enzymatic activity from residual host cell enzymes such as lipases esterases plays role for degradation. Their high activity, often at very low co...

objective(s):psoriasis is an autoimmune disease that appears on the skin. although psoriasis is clinically and histologically well characterized, its pathogenesis is unknown in detail. the aims of this study were to evaluate the proteome of psoriatic patients' sera and to compare them with those of normal healthy human to find valuable biomarkers. materials and methods: in a case-control s...