Abstract The cellular pool of RNA is immensely diverse and complex. During their biosynthesis, molecules undergo a vast number co- posttranscriptional processing modification steps. A unique example the non-conventional splicing RNAs. This protein-catalysed mechanism an essential step during tRNA maturation main mode endoplasmic reticulum (ER) stress signalling. Here, I discuss roles catalytic ...

mitochondria play key roles in many cell functions including energy production, fatty acid metabolism, pyrimidine biosynthesis, calcium homeostasis, and aging. they also regulate crucial signaling cascades such as apoptosis and oxidative stress. the proteome is often used to investigate the functional correlations on protein levels. based upon the human, genome there is estimated 2000 to 2500 a...

gbss protein, that is the product of waxy gene (wx) is one of the major enzyme in starch biosynthesis that controls the proportion of amylose to amylopechtine and its absence leads to production of starch with low amylose and higher amylopechtine content, called waxy starch.wx-a1, wx-b1, wx-d1 are three locuses in bread wheat (triticum aestivum) genome that encodes gbss protein and waxy starch ...

RNA molecules have key roles in many essential biological processes, including protein synthesis, transcriptional regulation, mRNA splicing and retroviral replication. The structural diversity of RNA, together with the lack of known RNA repair mechanisms, make RNA a challenging and important target for therapeutic intervention [1]. Our understanding of the modes by which RNA is recognized by li...

Although translation is the key step during gene expression, it remains poorly characterized at the level of individual genes. For this reason, we developed Transimulation - a web service measuring translational activity of genes in three model organisms: Escherichia coli, Saccharomyces cerevisiae and Homo sapiens. The calculations are based on our previous computational model of translation an...

Bilberry (Vaccinium myrtillus L.), rich in polyphenols, has been claimed to have lipid-lowering effects, but its underlying mechanisms remain unclear. The effects of bilberry extract (BE) with antioxidant properties on hepatic lipid metabolism were investigated by measuring the genes for cholesterol biosynthesis and flux HepG2 cells. mRNA protein levels involved such as sterol regulatory elemen...

Photosynthesis is an essential biological process and a key approach for raising crop yield. However, photosynthesis in rice not fully investigated. This study reported the photosynthetic properties transcriptomic profiles of chlorophyll (Chl) b-deficient mutant (ch11) wild-type (Oryza sativa L.). Chl revealed irregular chloroplast development (indistinct membranes, loss starch granules, thinne...

The phytopathogenic fungus Fusarium mangiferae belongs to the fujikuroi species complex (FFSC). Members of this group cause a wide spectrum devastating diseases on diverse agricultural crops. F. is causal agent mango malformation disease (MMD) and as such detrimental for agriculture in southern hemisphere. During plant infection, produces plethora bioactive secondary metabolites (SMs), which mo...